Järås, Marcus

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

Krönke, J., Fink, E. C., Hollenbach, P. W., MacBeth, K. J., Hurst, S. N., Udeshi, N. D., Chamberlain, P. P., Mani, D. R., Man, H. W., Gandhi, A. K., et al. (2015) · Nature

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 863

Core circadian clock genes regulate leukemia stem cells in AML

Puram, R. V., Kowalczyk, M. S., de Boer, C. G., Schneider, R. K., Miller, P. G., McConkey, M., Tothova, Z., Tejero, H., Heckl, D., Järås, M., et al. (2016) · Cell

Circadian rhythm and melatoninAcute Myeloid Leukemia Research

Cited by 274

Role of Casein Kinase 1A1 in the Biology and Targeted Therapy of del(5q) MDS

Schneider, R. K., Ademà, V., Heckl, D., Järås, M., Mallo, M., Lord, A. M., Chu, L. P., McConkey, M. E., Kramann, R., Mullally, A., et al. (2014) · Cancer Cell

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 188

Selective killing of candidate AML stem cells by antibody targeting of IL1RAP

Askmyr, M., Ågerstam, H., Hansen, N., Gordon, S., Arvanitakis, A., Rissler, M., Juliusson, G., Richter, J., Järås, M., & Fioretos, T. (2013) · Blood

Acute Myeloid Leukemia ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 127

IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

Ågerstam, H., Hansen, N., von Palffy, S., Sandén, C., Reckzeh, K., Karlsson, C., Lilljebjörn, H., Landberg, N., Askmyr, M., Högberg, C., et al. (2016) · Blood

Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia Research

Cited by 98

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia

Järås, M., Miller, P. G., Chu, L. P., Puram, R. V., Fink, E. C., Schneider, R. K., Al-Shahrour, F., Peña, P., Breyfogle, L. J., Hartwell, K. A., et al. (2014) · Journal of Experimental Medicine

Acute Myeloid Leukemia ResearchCancer-related Molecular Pathways

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