Quaranta, Vito

Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

Giannelli, G., Falk-Marzillier, J., Schiraldi, O., Stetler-Stevenson, W. G., & Quaranta, V. (1997) · Science

Protease and Inhibitor MechanismsCell Adhesion Molecules Research

Cited by 1,221

Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution

Schenk, S., Hintermann, E., Bilban, M., Koshikawa, N., Hojilla, C., Khokha, R., & Quaranta, V. (2003) · The Journal of Cell Biology

Protease and Inhibitor MechanismsCell Adhesion Molecules Research

Cited by 309

Quantifying drug combination synergy along potency and efficacy axes

Meyer, C. T., Wooten, D. J., Paudel, B. B., Bauer, J., Hardeman, K. N., Westover, D., Lovly, C. M., Harris, L. A., Tyson, D. R., & Quaranta, V. (2019) · Cell Systems

Computational Drug Discovery MethodsLung Cancer Treatments and Mutations

Cited by 202

MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery

Wooten, D. J., Meyer, C. T., Lubbock, A. L. R., Quaranta, V., & Lopez, C. F. (2021) · Nature Communications

Computational Drug Discovery Methodsthermodynamics and calorimetric analyses

Cited by 97

An unbiased metric of antiproliferative drug effect in vitro

Harris, L. A., Frick, P. L., Garbett, S. P., Hardeman, K. N., Paudel, B. B., Lopez, C. F., Quaranta, V., & Tyson, D. R. (2016) · Nature Methods

Animal testing and alternativesComputational Drug Discovery Methods

Cited by 92

Activation of αvβ3Integrin on Human Osteoclast-like Cells Stimulates Adhesion and Migration in Response to Osteopontin

Faccio, R., Grano, M., Colucci, S., Zallone, A. Z., Quaranta, V., & Pelletier, A. J. (1998) · Biochemical and Biophysical Research Communications

Cell Adhesion Molecules ResearchBone Metabolism and Diseases

Cited by 64