Keane, Pearse A.

Clinically applicable deep learning for diagnosis and referral in retinal disease

De Fauw, J., Ledsam, J. R., Romera-Paredes, B., Nikolov, S., Tomasev, N., Blackwell, S., Askham, H., Glorot, X., O’Donoghue, B., Visentin, D., et al. (2018) · Nature Medicine

Retinal Imaging and AnalysisRetinal Diseases and Treatments

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A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis

Liu, X., Faes, L., Kale, A. U., Wagner, S. K., Fu, D. J., Bruynseels, A., Mahendiran, T., Moraes, G., Shamdas, M., Kern, C., et al. (2019) · The Lancet Digital Health

Artificial Intelligence in Healthcare and EducationAI in cancer detection

Cited by 1,883

The Lancet Global Health Commission on Global Eye Health: vision beyond 2020

Burton, M. J., Ramke, J., Marques, A. P., Bourne, R. R. A., Congdon, N., Jones, I., Ah Tong, B. A. M., Arunga, S., Bachani, D., Bascaran, C., et al. (2021) · The Lancet Global Health

Ophthalmology and Visual Impairment StudiesGlaucoma and retinal disorders

Cited by 1,624

Artificial intelligence and deep learning in ophthalmology

Ting, D. S. W., Pasquale, L. R., Peng, L., Campbell, J. P., Lee, A. Y., Raman, R., Tan, G. S. W., Schmetterer, L., Keane, P. A., & Wong, T. Y. (2019) · British Journal of Ophthalmology

Retinal Imaging and AnalysisArtificial Intelligence in Healthcare and Education

Cited by 1,554

Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI

Vasey, B., Nagendran, M., Campbell, B., Clifton, D. A., Collins, G. S., Denaxas, S., Denniston, A. K., Faes, L., Geerts, B., Ibrahim, M., et al. (2022) · Nature Medicine

Artificial Intelligence in Healthcare and EducationMeta-analysis and systematic reviews

Cited by 1,039

A foundation model for generalizable disease detection from retinal images

Zhou, Y., Chia, M. A., Wagner, S. K., Ayhan, M. S., Williamson, D. J., Struyven, R. R., Liu, T., Xu, M., Lozano, M. G., Woodward-Court, P., et al. (2023) · Nature

Retinal Imaging and AnalysisOphthalmology and Visual Health Research

Cited by 1,014

Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension

Liu, X., Cruz Rivera, S., Moher, D., Calvert, M. J., Denniston, A. K., Ashrafian, H., Beam, A. L., Chan, A.-W., Collins, G. S., Deeks, A. D. J., et al. (2020) · The Lancet Digital Health

Meta-analysis and systematic reviewsArtificial Intelligence in Healthcare and Education

Cited by 555

Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension

Cruz Rivera, S., Liu, X., Chan, A.-W., Denniston, A. K., Calvert, M. J., Ashrafian, H., Beam, A. L., Collins, G. S., Darzi, A., Deeks, J. J., et al. (2020) · The Lancet Digital Health

Meta-analysis and systematic reviewsArtificial Intelligence in Healthcare and Education

Cited by 486

With an eye to AI and autonomous diagnosis

Keane, P. A., & Topol, E. J. (2018) · npj Digital Medicine

Retinal Imaging and AnalysisArtificial Intelligence in Healthcare and Education

Cited by 304

Predicting conversion to wet age-related macular degeneration using deep learning

Yim, J., Chopra, R., Spitz, T., Winkens, J., Obika, A., Kelly, C., Askham, H., Lukic, M., Huemer, J., Fasler, K., et al. (2020) · Nature Medicine

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 297

Integrated image-based deep learning and language models for primary diabetes care

Li, J., Guan, Z., Wang, J., Cheung, C. Y., Zheng, Y., Lim, L.-L., Lim, C. C., Ruamviboonsuk, P., Raman, R., Corsino, L., et al. (2024) · Nature Medicine

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 250

Stakeholder Perspectives of Clinical Artificial Intelligence Implementation: Systematic Review of Qualitative Evidence

Hogg, H. D. J., Al-Zubaidy, M., Technology Enhanced Macular Services Study Reference Group, Talks, J., Denniston, A. K., Kelly, C. J., Malawana, J., Papoutsi, C., Teare, M. D., Keane, P. A., et al. (2023) · Journal of Medical Internet Research

Artificial Intelligence in Healthcare and EducationHealth Policy Implementation Science

Cited by 163

A Clinician's Guide to Artificial Intelligence: How to Critically Appraise Machine Learning Studies

Faes, L., Liu, X., Wagner, S. K., Fu, D. J., Balaskas, K., Sim, D. A., Bachmann, L. M., Keane, P. A., & Denniston, A. K. (2020) · Translational Vision Science & Technology

Artificial Intelligence in Healthcare and EducationArtificial Intelligence in Healthcare

Cited by 162

Quantitative Subanalysis of Optical Coherence Tomography after Treatment with Ranibizumab for Neovascular Age-Related Macular Degeneration

Keane, P. A., Liakopoulos, S., Ongchin, S. C., Heussen, F. M., Msutta, S., Chang, K. T., Walsh, A. C., & Sadda, S. R. (2008) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsRetinal and Macular Surgery

Cited by 145

Predicting optical coherence tomography-derived diabetic macular edema grades from fundus photographs using deep learning

Varadarajan, A. V., Bavishi, P., Ruamviboonsuk, P., Chotcomwongse, P., Venugopalan, S., Narayanaswamy, A., Cuadros, J., Kanai, K., Bresnick, G., Tadarati, M., et al. (2020) · Nature Communications

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 139

Implementation of a cloud-based referral platform in ophthalmology: making telemedicine services a reality in eye care

Kern, C., Fu, D. J., Kortuem, K., Huemer, J., Barker, D., Davis, A., Balaskas, K., Keane, P. A., McKinnon, T., & Sim, D. A. (2020) · British Journal of Ophthalmology

Healthcare Systems and TechnologyTelemedicine and Telehealth Implementation

Cited by 97

Protecting Data Privacy in the Age of AI-Enabled Ophthalmology

Tom, E., Keane, P. A., Blazes, M., Pasquale, L. R., Chiang, M. F., Lee, A. Y., Lee, C. S., & and AAO Artificial Intelligence Task Force (2020) · Translational Vision Science & Technology

Artificial Intelligence in Healthcare and EducationPrivacy-Preserving Technologies in Data

Cited by 92

Intravitreal injections: past trends and future projections within a UK tertiary hospital

Chopra, R., Preston, G. C., Keenan, T. D. L., Mulholland, P., Patel, P. J., Balaskas, K., Hamilton, R. D., & Keane, P. A. (2022) · Eye

Retinal Diseases and TreatmentsRetinal and Macular Surgery

Cited by 83

AI-induced never-skilling in medical education

Ke, Y., Jin, L., Ong, J. C. L., Thirunavukarasu, A. J., Car, J., Cheung, C. Y., Tham, Y. C., Ting, D. S. W., Ong, M. E. H., Compton, S., et al. (2026) · Nature Medicine

Artificial Intelligence in Healthcare and EducationInnovations in Medical Education

Cited by 71

Health Economic and Safety Considerations for Artificial Intelligence Applications in Diabetic Retinopathy Screening

Xie, Y., Gunasekeran, D. V., Balaskas, K., Keane, P. A., Sim, D. A., Bachmann, L. M., Macrae, C., & Ting, D. S. W. (2020) · Translational Vision Science & Technology

Retinal Imaging and AnalysisArtificial Intelligence in Healthcare and Education

Cited by 59

Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines

Martindale, A. P. L., Llewellyn, C. D., de Visser, R. O., Ng, B., Ngai, V., Kale, A. U., di Ruffano, L. F., Golub, R. M., Collins, G. S., Moher, D., et al. (2024) · Nature Communications

Meta-analysis and systematic reviewsArtificial Intelligence in Healthcare and Education

Cited by 58

Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia

Tideman, J. W. L., Pärssinen, O., Haarman, A. E. G., Khawaja, A. P., Wedenoja, J., Williams, K. M., Biino, G., Ding, X., Kähönen, M., Lehtimäki, T., et al. (2021) · JAMA Ophthalmology

Ophthalmology and Visual Impairment StudiesGenetic Associations and Epidemiology

Cited by 56

RISK FACTORS FOR PROLIFERATIVE DIABETIC RETINOPATHY IN A LATINO AMERICAN POPULATION

Nittala, M. G., Keane, P. A., Zhang, K., & Sadda, S. R. (2014) · Retina

Retinal Diseases and TreatmentsDiabetes Management and Research

Cited by 55

Reinventing the eye exam

Keane, P., & Topol, E. (2019) · The Lancet

Ophthalmology and Visual Health ResearchRetinal Imaging and Analysis

Cited by 7