Palavicini, Juan Pablo

Senolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial

Gonzales, M. M., Garbarino, V. R., Kautz, T. F., Palavicini, J. P., Lopez-Cruzan, M., Dehkordi, S. K., Mathews, J. J., Zare, H., Xu, P., Zhang, B., et al. (2023) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 334

Senolytic therapy to modulate the progression of Alzheimer’s Disease (SToMP-AD) – Outcomes from the first clinical trial of senolytic therapy for Alzheimer's disease

Orr, M., Gonzales, M., Garbarino, V., Kautz, T., Palavicini, J., Lopez-Cruzan, M., Dehkordi, S. K., Mathews, J., Zare, H., Xu, P., et al. (2023) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 319

The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans

Palavicini, J. P., Chavez-Velazquez, A., Fourcaudot, M., Tripathy, D., Pan, M., Norton, L., DeFronzo, R. A., & Shannon, C. E. (2021) · Frontiers in Physiology

Lipid metabolism and biosynthesisAdipokines, Inflammation, and Metabolic Diseases

Cited by 36

Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease

Garbarino, V. R., Palavicini, J. P., Melendez, J., Barthelemy, N. R., He, Y., Kautz, T. F., Lopez-Cruzan, M., Mathews, J. J., Xu, P., Zhang, B., et al. (2025) · Neurotherapeutics

Alzheimer's disease research and treatmentsTelomeres, Telomerase, and Senescence

Cited by 26

Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain

Hopp, S. C., Rogers, J. G., Smith, S., Campos, G., Miller, H., Barannikov, S., Kuri, E. G., Wang, H., Han, X., Bieniek, K. F., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 4

PLCγ2 deficiency compromises systemic immune tolerance and erodes myelin homeostasis while enhancing oxidative metabolism in the mouse brain

Gutierrez-Kuri, E., Marie Garcia-Rogers, J. L., Perez, J., Smith, S., Kenwood, M. R., Archuleta, K. S., Xiao, Y., Campos, G., Barannikov, S., Wang, H., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 0