Dobbelstein, Matthias

Nucleo‐cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein

Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T., & Levine, A. J. (1998) · The EMBO Journal

Cancer-related Molecular PathwaysNuclear Structure and Function

Cited by 610

A polymorphic microsatellite that mediates induction of PIG3 by p53

Contente, A., Dittmer, A., Koch, M. C., Roth, J., & Dobbelstein, M. (2002) · Nature Genetics

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 274

p21/CDKN1A Mediates Negative Regulation of Transcription by p53

Löhr, K., Möritz, C., Contente, A., & Dobbelstein, M. (2003) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 227

Inactivation of the p53-homologue p73 by the mdm2-oncoprotein

Dobbelstein, M., Wienzek, S., König, C., & Roth, J. (1999) · Oncogene

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 161

Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity

Sriraman, A., Radovanovic, M., Wienken, M., Najafova, Z., Li, Y., & Dobbelstein, M. (2016) · Oncotarget

Cancer-related Molecular PathwaysProtein Tyrosine Phosphatases

Cited by 44

CDK4 inhibition diminishes p53 activation by MDM2 antagonists

Sriraman, A., Dickmanns, A., Najafova, Z., Johnsen, S. A., & Dobbelstein, M. (2018) · Cell Death & Disease

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 40

Usp22 deficiency impairs intestinal epithelial lineage specification in vivo

Kosinsky, R. L., Wegwitz, F., Hellbach, N., Dobbelstein, M., Mansouri, A., Vogel, T., Begus-Nahrmann, Y., & Johnsen, S. A. (2015) · Oncotarget

Epigenetics and DNA MethylationDevelopmental Biology and Gene Regulation

Cited by 34

Fortifying p53 – beyond Mdm2 inhibitors

Sriraman, A., Li, Y., & Dobbelstein, M. (2016) · Aging

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 6