Rodriguez, Raphaël

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

Rodriguez, R., Miller, K. M., Forment, J. V., Bradshaw, C. R., Nikan, M., Britton, S., Oelschlaegel, T., Xhemalce, B., Balasubramanian, S., & Jackson, S. P. (2012) · Nature Chemical Biology

DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties

Cited by 741

A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres

Rodriguez, R., Müller, S., Yeoman, J. A., Trentesaux, C., Riou, J.-F., & Balasubramanian, S. (2008) · Journal of the American Chemical Society

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 517

Chemical inhibition of NAT10 corrects defects of laminopathic cells

Larrieu, D., Britton, S., Demir, M., Rodriguez, R., & Jackson, S. P. (2014) · Science

Nuclear Structure and FunctionDNA Repair Mechanisms

Cited by 431

Activation of lysosomal iron triggers ferroptosis in cancer

Cañeque, T., Baron, L., Müller, S., Carmona, A., Colombeau, L., Versini, A., Solier, S., Gaillet, C., Sindikubwabo, F., Sampaio, J. L., et al. (2025) · Nature

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 287

Chemistry and biology of ferritin

Plays, M., Müller, S., & Rodriguez, R. (2021) · Metallomics

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 232

Click chemistry enables preclinical evaluation of targeted epigenetic therapies

Tyler, D. S., Vappiani, J., Cañeque, T., Lam, E. Y. N., Ward, A., Gilan, O., Chan, Y.-C., Hienzsch, A., Rutkowska, A., Werner, T., et al. (2017) · Science

Protein Degradation and InhibitorsClick Chemistry and Applications

Cited by 146