Cao, Xu

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

Tang, Y., Wu, X., Lei, W., Pang, L., Wan, C., Shi, Z., Zhao, L., Nagy, T. R., Peng, X., Hu, J., et al. (2009) · Nature Medicine

Bone Metabolism and DiseasesTGF-β signaling in diseases

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PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

Xie, H., Cui, Z., Wang, L., Xia, Z., Hu, Y., Xian, L., Li, C., Xie, L., Crane, J., Wan, M., et al. (2014) · Nature Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

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Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

Xian, L., Wu, X., Pang, L., Lou, M., Rosen, C. J., Qiu, T., Crane, J., Frassica, F., Zhang, L., Rodriguez, J. P., et al. (2012) · Nature Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

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Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain

Zhu, S., Zhu, J., Zhen, G., Hu, Y., An, S., Li, Y., Zheng, Q., Chen, Z., Yang, Y., Wan, M., et al. (2019) · Journal of Clinical Investigation

Osteoarthritis Treatment and MechanismsPain Mechanisms and Treatments

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Transforming growth factor‐β in stem cells and tissue homeostasis

Xu, X., Zheng, L., Yuan, Q., Zhen, G., Crane, J. L., Zhou, X., & Cao, X. (2018) · Bone Research

TGF-β signaling in diseasesLiver physiology and pathology

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Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis

Chen, H., Hu, B., Lv, X., Zhu, S., Zhen, G., Wan, M., Jain, A., Gao, B., Chai, Y., Yang, M., et al. (2019) · Nature Communications

Bone Metabolism and DiseasesBone health and osteoporosis research

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Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation

Morrell, A. E., Brown, G. N., Robinson, S. T., Sattler, R. L., Baik, A. D., Zhen, G., Cao, X., Bonewald, L. F., Jin, W., Kam, L. C., et al. (2018) · Bone Research

Bone Metabolism and DiseasesExtracellular vesicles in disease

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Reciprocal Roles of Msx2 in Regulation of Osteoblast and Adipocyte Differentiation

Ichida, F., Nishimura, R., Hata, K., Matsubara, T., Ikeda, F., Hisada, K., Yatani, H., Cao, X., Komori, T., Yamaguchi, A., et al. (2004) · Journal of Biological Chemistry

Bone Metabolism and DiseasesDevelopmental Biology and Gene Regulation

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Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow

Liu, X., Gu, Y., Kumar, S., Amin, S., Guo, Q., Wang, J., Fang, C.-L., Cao, X., & Wan, M. (2023) · Cell Metabolism

Telomeres, Telomerase, and SenescenceBone Metabolism and Diseases

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Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation

Yuan, X., Cao, J., He, X., Serra, R., Qu, J., Cao, X., & Yang, S. (2016) · Nature Communications

Hedgehog Signaling Pathway StudiesGenetic and Kidney Cyst Diseases

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Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis

Liu, X., Chai, Y., Liu, G., Su, W., Guo, Q., Lv, X., Gao, P., Yu, B., Ferbeyre, G., Cao, X., et al. (2021) · Nature Communications

Bone Metabolism and DiseasesTelomeres, Telomerase, and Senescence

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Programmed cell senescence in skeleton during late puberty

Li, C., Chai, Y., Wang, L., Gao, B., Chen, H., Gao, P., Zhou, F.-Q., Luo, X., Crane, J. L., Yu, B., et al. (2017) · Nature Communications

Telomeres, Telomerase, and SenescenceMesenchymal stem cell research

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PGE2/EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib

Xue, P., Wang, S., Lyu, X., Wan, M., Li, X., Ma, L., Ford, N. C., Li, Y., Guan, Y., Ding, W., et al. (2021) · Bone Research

Spine and Intervertebral Disc PathologyPain Mechanisms and Treatments

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IGF-I induced phosphorylation of PTH receptor enhances osteoblast to osteocyte transition

Qiu, T., Crane, J. L., Xie, L., Xian, L., Xie, H., & Cao, X. (2018) · Bone Research

Bone Metabolism and DiseasesParathyroid Disorders and Treatments

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An antibody against Siglec-15 promotes bone formation and fracture healing by increasing TRAP+ mononuclear cells and PDGF-BB secretion

Zhen, G., Dan, Y., Wang, R., Dou, C., Guo, Q., Zarr, M., Liu, L. N., Chen, L., Deng, R., Li, Y., et al. (2021) · Bone Research

Bone Metabolism and DiseasesBone health and osteoporosis research

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Sialylation of TLR2 initiates osteoclast fusion

Dou, C., Zhen, G., Dan, Y., Wan, M., Limjunyawong, N., & Cao, X. (2022) · Bone Research

Bone Metabolism and DiseasesGlycosylation and Glycoproteins Research

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Serum amyloid P secreted by bone marrow adipocytes drives skeletal amyloidosis

Kumar, S., Song, K., Wang, J., Baghel, M. S., Zeng, Y., Shen, K., Zheng, J., Crane, J., Demehri, S., Gao, P., et al. (2025) · Nature Aging

Bone Metabolism and DiseasesTelomeres, Telomerase, and Senescence

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