Kievit, Paul

Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques

Kievit, P., Halem, H., Marks, D. L., Dong, J. Z., Glavas, M. M., Sinnayah, P., Pranger, L., Cowley, M. A., Grove, K. L., & Culler, M. D. (2013) · Diabetes

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 231

Use and importance of nonhuman Primates in metabolic disease research: current state of the field

Havel, P. J., Kievit, P., Comuzzie, A. G., & Bremer, A. A. (2017) · ILAR Journal

Animal testing and alternativesPrimate Behavior and Ecology

Cited by 75

Hypoimmune islets achieve insulin independence after allogeneic transplantation in a fully immunocompetent non-human primate

Hu, X., White, K., Young, C., Olroyd, A. G., Kievit, P., Connolly, A. J., Deuse, T., & Schrepfer, S. (2024) · Cell Stem Cell

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 73

FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys

Andersen, B., Straarup, E. M., Heppner, K. M., Takahashi, D. L., Raffaele, V., Dissen, G. A., Lewandowski, K., Bödvarsdottir, T. B., Raun, K., Grove, K. L., et al. (2018) · International Journal of Obesity

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 66

Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models

Rupp, A. C., Tomlinson, A. J., Affinati, A. H., Yacawych, W. T., Duensing, A. M., True, C., Lindsley, S. R., Kirigiti, M. A., MacKenzie, A., Polex-Wolf, J., et al. (2023) · Journal of Clinical Investigation

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 55

Whole transcriptome analysis and validation of metabolic pathways in subcutaneous adipose tissues during FGF21-induced weight loss in non-human primates

Murray, S. A., Dalbøge, L. S., Baquero, K., Sanford, C. A., Misquith, A., Mercer, A. J., Meek, T. H., Guldbrandt, M., Andersen, B., Kievit, P., et al. (2020) · Scientific Reports

Fibroblast Growth Factor ResearchAdipose Tissue and Metabolism

Cited by 12