Mathur, Vidhu

Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain

Marschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 1,414

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

Marschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2020) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 1,384

Ageing hallmarks exhibit organ-specific temporal signatures

Schaum, N., Lehallier, B., Hahn, O., Pálovics, R., Hosseinzadeh, S., Lee, S. E., Sit, R., Lee, D. P., Losada, P. M., Zardeneta, M. E., et al. (2020) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 671

Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1

Yousef, H., Czupalla, C. J., Lee, D., Chen, M. B., Burke, A. N., Zera, K. A., Zandstra, J., Berber, E., Lehallier, B., Mathur, V., et al. (2019) · Nature Medicine

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 442

Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation

Mathur, V., Burai, R., Vest, R. T., Bonanno, L. N., Lehallier, B., Zardeneta, M. E., Mistry, K. N., Do, D., Marsh, S. E., Abud, E. M., et al. (2017) · Neuron

interferon and immune responsesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 175

Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury

Holden, S. S., Grandi, F. C., Aboubakr, O., Higashikubo, B., Cho, F. S., Chang, A. H., Forero, A. O., Morningstar, A. R., Mathur, V., Kuhn, L. J., et al. (2021) · Science

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 133

Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer’s disease–like mice

Prokop, S., Miller, K. R., Drost, N., Handrick, S., Mathur, V., Luo, J., Wegner, A., Wyss-Coray, T., & Heppner, F. L. (2015) · Journal of Experimental Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 116