Hay, Ronald T.

Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity

Xirodimas, D. P., Saville, M. K., Bourdon, J.-C., Hay, R. T., & Lane, D. P. (2004) · Cell

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 570

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

Plechanovová, A., Jaffray, E. G., Tatham, M. H., Naismith, J. H., & Hay, R. T. (2012) · Nature

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 521

Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

Cockman, M. E., Lancaster, D. E., Stolze, I. P., Hewitson, K. S., McDonough, M. A., Coleman, M. L., Coles, C. H., Yu, X., Hay, R. T., Ley, S. C., et al. (2006) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysCancer, Hypoxia, and Metabolism

Cited by 285

SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage

Yin, Y., Seifert, A., Chua, J. S., Maure, J.-F., Golebiowski, F., & Hay, R. T. (2012) · Genes & Development

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 237

Role of cysteine62in DNA recognition by the P50 subunit of NF-xB

Matthews, J. R., Kaszubska, W., Turcatti, G., Wells, T. N. C., & Hay, R. T. (1993) · Nucleic Acids Research

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 147

Stable-isotope labeling with amino acids in nematodes

Larance, M., Bailly, A. P., Pourkarimi, E., Hay, R. T., Buchanan, G., Coulthurst, S., Xirodimas, D. P., Gartner, A., & Lamond, A. I. (2011) · Nature Methods

Advanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 120

P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2

Xirodimas, D. P., Chisholm, J., Desterro, J. M. S., Lane, D. P., & Hay, R. T. (2002) · FEBS Letters

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 94

Structural basis of BRCC36 function in DNA repair and immune regulation

Rabl, J., Bunker, R. D., Schenk, A. D., Cavadini, S., Gill, M. E., Abdulrahman, W., Andrés-Pons, A., Luijsterburg, M. S., Ibrahim, A. F. M., Branigan, E., et al. (2019) · Molecular Cell

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 84