Cassa, Christopher A.

Predictable and precise template-free CRISPR editing of pathogenic variants

Shen, M. W., Arbab, M., Hsu, J. Y., Worstell, D., Culbertson, S. J., Krabbe, O., Cassa, C. A., Liu, D. R., Gifford, D. K., & Sherwood, R. I. (2018) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 569

Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning

Arbab, M., Shen, M. W., Mok, B., Wilson, C., Matuszek, Ż., Cassa, C. A., & Liu, D. R. (2020) · Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 294

Identification of cis-suppression of human disease mutations by comparative genomics

Task Force for Neonatal Genomics, Jordan, D. M., Frangakis, S. G., Golzio, C., Cassa, C. A., Kurtzberg, J., Davis, E. E., Sunyaev, S. R., & Katsanis, N. (2015) · Nature

Genomics and Rare DiseasesGenomics and Phylogenetic Studies

Cited by 115

Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification

Ryu, J., Barkal, S., Yu, T., Jankowiak, M., Zhou, Y., Francoeur, M., Phan, Q. V., Li, Z., Tognon, M., Brown, L., et al. (2023) · Nature Genetics

CRISPR and Genetic EngineeringGenomics and Rare Diseases

Cited by 32

DeMAG predicts the effects of variants in clinically actionable genes by integrating structural and evolutionary epistatic features

Luppino, F., Adzhubei, I. A., Cassa, C. A., & Toth-Petroczy, A. (2023) · Nature Communications

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 12

DeMAG predicts the effects of variants in clinically actionable genes by integrating structural and evolutionary epistatic features

Luppino, F., Adzhubei, I. A., Cassa, C. A., & Toth-Petroczy, A. (2022) · Nature Communications

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 12