Savva, Christos G.

Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

Gruszczyk, J., Grandvuillemin, L., Lai-Kee-Him, J., Paloni, M., Savva, C. G., Germain, P., Grimaldi, M., Boulahtouf, A., Kwong, H.-S., Bous, J., et al. (2022) · Nature Communications

Heat shock proteins researchReceptor Mechanisms and Signaling

Cited by 137

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

Turnbull, R. E., Fairall, L., Saleh, A., Kelsall, E., Morris, K. L., Ragan, T. J., Savva, C. G., Chandru, A., Millard, C. J., Makarova, O. V., et al. (2020) · Nature Communications

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 108

Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO2

Brotherton, D. H., Nijjar, S., Savva, C. G., Dale, N., & Cameron, A. D. (2024) · eLife

Connexins and lens biologyIon channel regulation and function

Cited by 23

Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2

Brotherton, D. H., Nijjar, S., Savva, C. G., Dale, N., & Cameron, A. D. (2023) · eLife

Connexins and lens biologyIon channel regulation and function

Cited by 23

Structure of the human CTF18−RFC clamp loader bound to PCNA

Briola, G. R., Tehseen, M., Al-Amodi, A., Young, G., Danazumi, A. U., Nguyen, P. Q., Savva, C. G., Hedglin, M., Hamdan, S. M., & De Biasio, A. (2026) · eLife

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 2