Sandoval, Wendy

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., et al. (2018) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 907

NINJ1 mediates plasma membrane rupture during lytic cell death

Kayagaki, N., Kornfeld, O. S., Lee, B. L., Stowe, I. B., O’Rourke, K., Li, Q., Sandoval, W., Yan, D., Kang, J., Xu, M., et al. (2021) · Nature

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 857

In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice.

Browder, K. C., Reddy, P., Yamamoto, M., Haghani, A., Guillen, I. G., Sahu, S., Wang, C., Luque, Y., Prieto, J., Shi, L., et al. (2022) · Nature Aging

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 253

Disruption of IRE1α through its kinase domain attenuates multiple myeloma

Harnoss, J. M., Le Thomas, A., Shemorry, A., Marsters, S. A., Lawrence, D. A., Lu, M., Chen, Y.-C. A., Qing, J., Totpal, K., Kan, D., et al. (2019) · Proceedings of the National Academy of Sciences

Endoplasmic Reticulum Stress and DiseaseMultiple Myeloma Research and Treatments

Cited by 109

The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function

Oberbeck, N., Pham, V. C., Webster, J. D., Reja, R., Huang, C. S., Zhang, Y., Roose-Girma, M., Warming, S., Li, Q., Birnberg, A., et al. (2019) · Nature

Skin and Cellular Biology ResearchGenetic and rare skin diseases.

Cited by 86

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Zammit, N. W., Siggs, O. M., Gray, P. E., Horikawa, K., Langley, D. B., Walters, S. N., Daley, S. R., Loetsch, C., Warren, J., Yap, J. Y., et al. (2019) · Nature Immunology

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 80

Efficient production of bispecific IgG of different isotypes and species of origin in single mammalian cells

Dillon, M., Yin, Y., Zhou, J., McCarty, L., Ellerman, D., Slaga, D., Junttila, T. T., Han, G., Sandoval, W., Ovacik, M. A., et al. (2017) · mAbs

Monoclonal and Polyclonal Antibodies ResearchViral Infectious Diseases and Gene Expression in Insects

Cited by 75

Exposing the molecular heterogeneity of glycosylated biotherapeutics

Schachner, L., Mullen, C., Phung, W., Hinkle, J., Beardsley, M. I., Bentley, T., Day, P., Tsai, C., Sukumaran, S., Baginski, T., et al. (2023) · Nature Communications

Mass Spectrometry Techniques and ApplicationsGlycosylation and Glycoproteins Research

Cited by 37

Exposing the molecular heterogeneity of glycosylated biotherapeutics

Schachner, L. F., Mullen, C., Phung, W., Hinkle, J. D., Beardsley, M. I., Bentley, T., Day, P., Tsai, C., Sukumaran, S., Baginski, T., et al. (2023) · Nature Communications

Mass Spectrometry Techniques and ApplicationsGlycosylation and Glycoproteins Research

Cited by 36

Exposing the molecular heterogeneity of glycosylated biotherapeutics

Schachner, L. F., Mullen, C., Phung, W., Hinkle, J. D., Beardsley, M. I., Bentley, T., Day, P., Tsai, C., Sukumaran, S., Baginski, T., et al. (2024) · Nature Communications

Mass Spectrometry Techniques and ApplicationsGlycosylation and Glycoproteins Research

Cited by 36

Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimer’s Disease and Multiple Sclerosis

Etxeberria, A., Shen, Y.-A. A., Vito, S., Silverman, S. M., Imperio, J., Lalehzadeh, G., Soung, A. L., Du, C., Xie, L., Choy, M. K., et al. (2024) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 34