Ramachandran, Prakash

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

Ramachandran, P., Dobie, R., Wilson-Kanamori, J. R., Dora, E. F., Henderson, B. E. P., Luu, N. T., Portman, J. R., Matchett, K. P., Brice, M., Marwick, J. A., et al. (2019) · Nature

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 1,784

Liver fibrosis and repair: Immune regulation of wound healing in a solid organ

Pellicoro, A., Ramachandran, P., Iredale, J. P., & Fallowfield, J. A. (2014) · Nature Reviews Immunology

Liver physiology and pathologyWound Healing and Treatments

Cited by 1,310

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

Ramachandran, P., Pellicoro, A., Vernon, M. A., Boulter, L., Aucott, R. L., Ali, A., Hartland, S. N., Snowdon, V. K., Cappon, A., Gordon-Walker, T. T., et al. (2012) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyCardiac Fibrosis and Remodeling

Cited by 1,001

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

Boulter, L., Govaere, O., Bird, T. G., Radulescu, S., Ramachandran, P., Pellicoro, A., Ridgway, R. A., Seo, S. S., Spee, B., Van Rooijen, N., et al. (2012) · Nature Medicine

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

Cited by 747

Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis

Gibbons, M. A., MacKinnon, A. C., Ramachandran, P., Dhaliwal, K., Duffin, R., Phythian-Adams, A. T., van Rooijen, N., Haslett, C., Howie, S. E., Simpson, A. J., et al. (2011) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTransplantation: Methods and Outcomes

Cited by 466

Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis

Dobie, R., Wilson-Kanamori, J. R., Henderson, B. E. P., Smith, J. R., Matchett, K. P., Portman, J. R., Wallenborg, K., Picelli, S., Zagorska, A., Pendem, S. V., et al. (2019) · Cell Reports

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 420

Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function

Thomas, J. A., Pope, C., Wojtacha, D., Robson, A. J., Gordon-Walker, T. T., Hartland, S., Ramachandran, P., Van Deemter, M., Hume, D. A., Iredale, J. P., et al. (2011) · Hepatology

Liver physiology and pathologyMesenchymal stem cell research

Cited by 346

Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis

Ramachandran, P., Matchett, K. P., Dobie, R., Wilson-Kanamori, J. R., & Henderson, N. C. (2020) · Nature Reviews Gastroenterology & Hepatology

Single-cell and spatial transcriptomicsLiver physiology and pathology

Cited by 253

Immunology of human fibrosis

Bhattacharya, M., & Ramachandran, P. (2023) · Nature Immunology

Cardiac Fibrosis and RemodelingInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 148

Multimodal decoding of human liver regeneration

Matchett, K., Wilson-Kanamori, Jr., Portman, Jr., Kapourani, C., Fercoq, F., May, S., Mackey, J., Brice, M., Zajdel, E., Beltran, M., et al. (2023) · Nature

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 140

Multimodal decoding of human liver regeneration

Matchett, K. P., Wilson-Kanamori, J. R., Portman, J. R., Kapourani, C. A., Fercoq, F., May, S., Zajdel, E., Beltran, M., Sutherland, E. F., Mackey, J. B. G., et al. (2024) · Nature

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 140

Resolution of Liver Fibrosis: Basic Mechanisms and Clinical Relevance

Ramachandran, P., Iredale, J., & Fallowfield, J. (2015) · Seminars in Liver Disease

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 129

Macrophages: Central regulators of hepatic fibrogenesis and fibrosis resolution

Ramachandran, P., & Iredale, J. P. (2012) · Journal of Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 113

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

Kotsiliti, E., Leone, V., Schuehle, S., Govaere, O., Li, H., Wolf, M. J., Horvatic, H., Bierwirth, S., Hundertmark, J., Inverso, D., et al. (2023) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 108

Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis

Kimura, N., Wong, M. C., Hardisty, G., Higgins, B., Huang, P.-C., Besh, M., Patten, D. A., Kendall, T., Ramachandran, P., Rossi, A. G., et al. (2025) · Cell Reports

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 3