Jiang, Fuguo

CRISPR–Cas9 Structures and Mechanisms

Jiang, F., & Doudna, J. A. (2017) · Annual Review of Biophysics

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Structures of Cas9 endonucleases reveal RNA-mediated conformational activation

Jinek, M., Jiang, F., Taylor, D. W., Sternberg, S. H., Kaya, E., Ma, E., Anders, C., Hauer, M., Zhou, K., Lin, S., et al. (2014) · Science

CRISPR and Genetic EngineeringEnzyme Structure and Function

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Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

Lee, K., Conboy, M., Park, H. M., Jiang, F., Kim, H. J., Dewitt, M. A., Mackley, V. A., Chang, K., Rao, A., Skinner, C., et al. (2017) · Nature Biomedical Engineering

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

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Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

Devarkar, S. C., Wang, C., Miller, M. T., Ramanathan, A., Jiang, F., Khan, A. G., Patel, S. S., & Marcotrigiano, J. (2016) · Proceedings of the National Academy of Sciences

interferon and immune responsesImmune Response and Inflammation

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Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

Isaac, R. S., Jiang, F., Doudna, J. A., Lim, W. A., Narlikar, G. J., & Almeida, R. (2016) · eLife

CRISPR and Genetic EngineeringGenomics and Chromatin Dynamics

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Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo

Park, H. M., Liu, H., Wu, J., Chong, A., Mackley, V., Fellmann, C., Rao, A., Jiang, F., Chu, H., Murthy, N., et al. (2018) · Nature Communications

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

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