Eckmann, Lars

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Greten, F. R., Eckmann, L., Greten, T. F., Park, J. M., Li, Z.-W., Egan, L. J., Kagnoff, M. F., & Karin, M. (2004) · Cell

NF-κB Signaling PathwaysSignaling Pathways in Disease

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IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

Grivennikov, S., Karin, E., Terzic, J., Mucida, D., Yu, G.-Y., Vallabhapurapu, S., Scheller, J., Rose-John, S., Cheroutre, H., Eckmann, L., et al. (2009) · Cancer Cell

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 2,155

Adenoma–linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

Grivennikov, S. I., Wang, K., Mucida, D., Stewart, C. A., Schnabl, B., Jauch, D., Taniguchi, K., Yu, G.-Y., Österreicher, C. H., Hung, K. E., et al. (2012) · Nature

Cancer Immunotherapy and BiomarkersIL-33, ST2, and ILC Pathways

Cited by 1,327

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

Vaishnava, S., Behrendt, C. L., Ismail, A. S., Eckmann, L., & Hooper, L. V. (2008) · Proceedings of the National Academy of Sciences

Immune Response and InflammationGut microbiota and health

Cited by 1,019

NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ

Greten, F. R., Arkan, M. C., Bollrath, J., Hsu, L.-C., Goode, J., Miething, C., Göktuna, S. I., Neuenhahn, M., Fierer, J., Paxian, S., et al. (2007) · Cell

NF-κB Signaling PathwaysInflammasome and immune disorders

Cited by 616

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

Zaph, C., Troy, A. E., Taylor, B. C., Berman-Booty, L. D., Guild, K. J., Du, Y., Yost, E. A., Gruber, A. D., May, M. J., Greten, F. R., et al. (2007) · Nature

IL-33, ST2, and ILC PathwaysImmune Response and Inflammation

Cited by 496

Gut‐liver axis at the frontier of host‐microbial interactions

Brandl, K., Kumar, V., & Eckmann, L. (2017) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 201

Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice

Mazagova, M., Wang, L., Anfora, A. T., Wissmueller, M., Lesley, S. A., Miyamoto, Y., Eckmann, L., Dhungana, S., Pathmasiri, W., Sumner, S., et al. (2015) · The FASEB Journal

Liver physiology and pathologyGut microbiota and health

Cited by 199

The fecal mycobiome in non-alcoholic fatty liver disease

Demir, M., Lang, S., Hartmann, P., Duan, Y., Martin, A., Miyamoto, Y., Bondareva, M., Zhang, X., Wang, Y., Kasper, P., et al. (2022) · Journal of Hepatology

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 197

Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes

Russell, B. J., Brown, S. D., Siguenza, N., Mai, I., Saran, A. R., Lingaraju, A., Maissy, E. S., Dantas Machado, A. C., Pinto, A. F. M., Sanchez, C., et al. (2022) · Cell

Bacterial Cancer TherapyGut microbiota and health

Cited by 151

α1-giardin based live heterologous vaccine protects against Giardia lamblia infection in a murine model

Jenikova, G., Hruz, P., Andersson, M. K., Tejman-Yarden, N., Ferreira, P. C. D., Andersen, Y. S., Davids, B. J., Gillin, F. D., Svärd, S. G., Curtiss, R., et al. (2011) · Vaccine

Parasitic Infections and DiagnosticsAmoebic Infections and Treatments

Cited by 49