Wei, Guanghong

Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell

Wei, G., Xi, W., Nussinov, R., & Ma, B. (2016) · Chemical Reviews

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 436

Green Tea Extracts EGCG and EGC Display Distinct Mechanisms in Disrupting Aβ42 Protofibril

Zhan, C., Chen, Y., Tang, Y., & Wei, G. (2020) · ACS Chemical Neuroscience

Alzheimer's disease research and treatmentsTea Polyphenols and Effects

Cited by 115

Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau

Siddiqua, A., Luo, Y., Meyer, V., Swanson, M. A., Yu, X., Wei, G., Zheng, J., Eaton, G. R., Ma, B., Nussinov, R., et al. (2012) · Journal of the American Chemical Society

Alzheimer's disease research and treatmentsElectron Spin Resonance Studies

Cited by 75

Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms

Weismiller, H. A., Murphy, R., Wei, G., Ma, B., Nussinov, R., & Margittai, M. (2018) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 44

Single Mutations in Tau Modulate the Populations of Fibril Conformers through Seed Selection

Meyer, V., Dinkel, P. D., Luo, Y., Yu, X., Wei, G., Zheng, J., Eaton, G. R., Ma, B., Nussinov, R., Eaton, S. S., et al. (2014) · Angewandte Chemie International Edition

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 42