Kakita, Akiyoshi

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

Zhou, Y., Song, W. M., Andhey, P. S., Swain, A., Levy, T., Miller, K. R., Poliani, P. L., Cominelli, M., Grover, S., Gilfillan, S., et al. (2020) · Nature Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 1,150

Structure-based classification of tauopathies

Shi, Y., Zhang, W., Yang, Y., Murzin, A. G., Falcon, B., Kotecha, A., van Beers, M., Tarutani, A., Kametani, F., Garringer, H. J., et al. (2021) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 878

TDP ‐ 43 mutation in familial amyotrophic lateral sclerosis

Yokoseki, A., Shiga, A., Tan, C., Tagawa, A., Kaneko, H., Koyama, A., Eguchi, H., Tsujino, A., Ikeuchi, T., Kakita, A., et al. (2008) · Annals of Neurology

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 373

Accumulation of α-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy

Wakabayashi, K., Hayashi, S., Kakita, A., Yamada, M., Toyoshima, Y., Yoshimoto, M., & Takahashi, H. (1998) · Acta Neuropathologica

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 347

Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions

Nishihira, Y., Tan, C.-F., Onodera, O., Toyoshima, Y., Yamada, M., Morita, T., Nishizawa, M., Kakita, A., & Takahashi, H. (2008) · Acta Neuropathologica

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 187

Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia

Koga, M., Ishiguro, H., Yazaki, S., Horiuchi, Y., Arai, M., Niizato, K., Iritani, S., Itokawa, M., Inada, T., Iwata, N., et al. (2009) · Human Molecular Genetics

Schizophrenia research and treatmentChromatin Remodeling and Cancer

Cited by 112

TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia

Zhang, H., Tan, C.-F., Mori, F., Tanji, K., Kakita, A., Takahashi, H., & Wakabayashi, K. (2007) · Acta Neuropathologica

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 111

Proteinase K-resistant α-synuclein is deposited in presynapses in human Lewy body disease and A53T α-synuclein transgenic mice

Tanji, K., Mori, F., Mimura, J., Itoh, K., Kakita, A., Takahashi, H., & Wakabayashi, K. (2010) · Acta Neuropathologica

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 102

Keap1 is localized in neuronal and glial cytoplasmic inclusions in various neurodegenerative diseases

Tanji, K., Maruyama, A., Odagiri, S., Mori, F., Itoh, K., Kakita, A., Takahashi, H., & Wakabayashi, K. (2013) · Journal of Neuropathology & Experimental Neurology

Genomics, phytochemicals, and oxidative stressParkinson's Disease Mechanisms and Treatments

Cited by 80

Characteristic microglial features in patients with hereditary diffuse leukoencephalopathy with spheroids

Tada, M., Konno, T., Tada, M., Tezuka, T., Miura, T., Mezaki, N., Okazaki, K., Arakawa, M., Itoh, K., Yamamoto, T., et al. (2016) · Annals of Neurology

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 70

Lack of Genetic Association Between TREM2 and Late-Onset Alzheimer's Disease in a Japanese Population

Miyashita, A., Wen, Y., Kitamura, N., Matsubara, E., Kawarabayashi, T., Shoji, M., Tomita, N., Furukawa, K., Arai, H., Asada, T., et al. (2014) · Journal of Alzheimer’s Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 69

Enhanced Accumulation of Phosphorylated α-Synuclein and Elevated β-Amyloid 42/40 Ratio Caused by Expression of the Presenilin-1 ΔT440 Mutant Associated with Familial Lewy Body Disease and Variant Alzheimer's Disease

Kaneko, H., Kakita, A., Kasuga, K., Nozaki, H., Ishikawa, A., Miyashita, A., Kuwano, R., Ito, G., Iwatsubo, T., Takahashi, H., et al. (2007) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 44

Brain expression level and activity of HDAC6 protein in neurodegenerative dementia

Odagiri, S., Tanji, K., Mori, F., Miki, Y., Kakita, A., Takahashi, H., & Wakabayashi, K. (2013) · Biochemical and Biophysical Research Communications

Alzheimer's disease research and treatmentsHistone Deacetylase Inhibitors Research

Cited by 43

Association of rare APOE missense variants with Alzheimer's disease in the Japanese population

Miyashita, A., Obinata, A., Hara, N., Mitsumori, R., Kaneda, D., Hashizume, Y., Sano, T., Takao, M., Gabdulkhaev, R., Tada, M., et al. (2025) · Journal of Alzheimer’s Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 5