Harkin, Andrew

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

Beumer, W., Gibney, S. M., Drexhage, R. C., Pont-Lezica, L., Doorduin, J., Klein, H. C., Steiner, J., Connor, T. J., Harkin, A., Versnel, M. A., et al. (2012) · Journal of Leukocyte Biology

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 347

Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism

Gigliucci, V., O’Dowd, G., Casey, S., Egan, D., Gibney, S., & Harkin, A. (2013) · Psychopharmacology

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 177

Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration

O'Sullivan, J. B., Ryan, K. M., Curtin, N. M., Harkin, A., & Connor, T. J. (2009) · The International Journal of Neuropsychopharmacology

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 146

DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic-pituitary-adrenal axis activity and to early life emotional abuse

Farrell, C., Doolin, K., O’ Leary, N., Jairaj, C., Roddy, D., Tozzi, L., Morris, D., Harkin, A., Frodl, T., Nemoda, Z., et al. (2018) · Psychiatry Research

Stress Responses and CortisolEpigenetics and DNA Methylation

Cited by 144

Altered tryptophan catabolite concentrations in major depressive disorder and associated changes in hippocampal subfield volumes

Doolin, K., Allers, K. A., Pleiner, S., Liesener, A., Farrell, C., Tozzi, L., O’Hanlon, E., Roddy, D., Frodl, T., Harkin, A., et al. (2018) · Psychoneuroendocrinology

Tryptophan and brain disordersTreatment of Major Depression

Cited by 89

Psychedelic therapy's transdiagnostic effects: A research domain criteria (RDoC) perspective

Kelly, J. R., Gillan, C. M., Prenderville, J., Kelly, C., Harkin, A., Clarke, G., & O'Keane, V. (2021) · Frontiers in Psychiatry

Psychedelics and Drug StudiesTreatment of Major Depression

Cited by 69

Expression of glucocorticoid inducible genes is associated with reductions in cornu ammonis and dentate gyrus volumes in patients with major depressive disorder

Frodl, T., Carballedo, A., Frey, E.-M., O'Keane, V., Skokauskas, N., Morris, D., Gill, M., Hughes, M. M., Harkin, A., & Connor, T. (2014) · Development and Psychopathology

Stress Responses and CortisolTreatment of Major Depression

Cited by 20