Breen, Gerome

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

Sniekers, S., Stringer, S., Watanabe, K., Jansen, P. R., Coleman, J. R. I., Krapohl, E., Taskesen, E., Hammerschlag, A. R., Okbay, A., Zabaneh, D., et al. (2017) · Nature Genetics

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 490

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Study, S. S., Singh, T., Study, I., Study, D., UK10 K Consortium, Kurki, M. I., Curtis, D., Purcell, S. M., Crooks, L., McRae, J., et al. (2016) · Nature Neuroscience

Schizophrenia research and treatmentGenomics and Rare Diseases

Cited by 452

Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors’ and Longitudinal ‘Targets’

Cattaneo, A., Gennarelli, M., Uher, R., Breen, G., Farmer, A., Aitchison, K. J., Craig, I. W., Anacker, C., Zunsztain, P. A., McGuffin, P., et al. (2013) · Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 436

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

Thambisetty, M., Simmons, A., Velayudhan, L., Hye, A., Campbell, J., Zhang, Y., Wahlund, L.-O., Westman, E., Kinsey, A., Güntert, A., et al. (2010) · Archives of General Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 405

An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation

Hannon, E., Dempster, E., Viana, J., Burrage, J., Smith, A. R., Macdonald, R., St Clair, D., Mustard, C., Breen, G., Therman, S., et al. (2016) · Genome Biology

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 349

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

MDD Working Group of the Psychiatric Genomics Consortium, Cai, N., Revez, J. A., Adams, M. J., Andlauer, T. F. M., Breen, G., Byrne, E. M., Clarke, T.-K., Forstner, A. J., Grabe, H. J., et al. (2020) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 344

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., et al. (2019) · American Journal of Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 270

Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study

Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., et al. (2019) · JAMA Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 240

Genetic association of major depression with atypical features and obesity-related immunometabolic dysregulations

Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., et al. (2017) · JAMA Psychiatry

Genetic Associations and EpidemiologyTryptophan and brain disorders

Cited by 233

The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression

Kohli, M. A., Lucae, S., Saemann, P. G., Schmidt, M. V., Demirkan, A., Hek, K., Czamara, D., Alexander, M., Salyakina, D., Ripke, S., et al. (2011) · Neuron

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 228

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway

Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., Lourdusamy, A., Furney, S., et al. (2014) · Molecular Psychiatry

Alzheimer's disease research and treatmentsClusterin in disease pathology

Cited by 222

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., et al. (2020) · Biological Psychiatry

Genetic Associations and EpidemiologyBipolar Disorder and Treatment

Cited by 199

A meta-analysis of cytokine concentrations in eating disorders

Dalton, B., Bartholdy, S., Robinson, L., Solmi, M., Ibrahim, M. A. A., Breen, G., Schmidt, U., & Himmerich, H. (2018) · Journal of Psychiatric Research

Eating Disorders and BehaviorsTryptophan and brain disorders

Cited by 197

GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors

Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J., Murnyak, B., Wendt, F., Adams, M., et al. (2023) · American Journal of Psychiatry

Genetic Associations and EpidemiologySuicide and Self-Harm Studies

Cited by 160

UK-Wide Surveillance of Neurological and Neuropsychiatric Complications of COVID-19: The First 153 Patients

Varatharaj, A., Thomas, N., Ellul, M., Davies, N. W., Pollak, T., Tenorio, E. L., Sultan, M., Easton, A., Breen, G., Zandi, M., et al. (2020) · SSRN Electronic Journal

Long-Term Effects of COVID-19Infectious Encephalopathies and Encephalitis

Cited by 160

Whole genome linkage scan of recurrent depressive disorder from the depression network study

McGuffin, P., Knight, J., Breen, G., Brewster, S., Boyd, P. R., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., et al. (2005) · Human Molecular Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 159

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer’s disease

Furney, S. J., Simmons, A., Breen, G., Pedroso, I., Lunnon, K., Proitsi, P., Hodges, A., Powell, J., Wahlund, L.-O., Kloszewska, I., et al. (2011) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 157

Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders

Tropeano, M., Ahn, J. W., Dobson, R. J. B., Breen, G., Rucker, J., Dixit, A., Pal, D. K., McGuffin, P., Farmer, A., White, P. S., et al. (2013) · PLoS ONE

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 154

Clinical predictors of response to cognitive-behavioral therapy in pediatric anxiety disorders: the Genes for Treatment (GxT) Study

Hudson, J. L., Keers, R., Roberts, S., Coleman, J. R. I., Breen, G., Arendt, K., Bögels, S., Cooper, P., Creswell, C., Hartman, C., et al. (2015) · Journal of the American Academy of Child & Adolescent Psychiatry

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesChild and Adolescent Psychosocial and Emotional Development

Cited by 150

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., et al. (2019) · Nature Communications

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 143

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K. V., Balsevich, G., Schmidt, M. V., Karbalai, N., Czamara, D., et al. (2015) · Neuron

Stress Responses and CortisolGenetic Associations and Epidemiology

Cited by 142

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

Hannon, E., Dempster, E. L., Mansell, G., Burrage, J., Bass, N., Bohlken, M. M., Corvin, A., Curtis, C. J., Dempster, D., Di Forti, M., et al. (2021) · eLife

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 132

A Genome-Wide Test of the Differential Susceptibility Hypothesis Reveals a Genetic Predictor of Differential Response to Psychological Treatments for Child Anxiety Disorders

Keers, R., Coleman, J. R. I., Lester, K. J., Roberts, S., Breen, G., Thastum, M., Bögels, S., Schneider, S., Heiervang, E., Meiser-Stedman, R., et al. (2016) · Psychotherapy and Psychosomatics

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesChild and Adolescent Psychosocial and Emotional Development

Cited by 127

Serotonin tranporter methylation and response to cognitive behaviour therapy in children with anxiety disorders

Roberts, S., Lester, K. J., Hudson, J. L., Rapee, R. M., Creswell, C., Cooper, P. J., Thirlwall, K. J., Coleman, J. R. I., Breen, G., Wong, C. C. Y., et al. (2014) · Translational Psychiatry

Epigenetics and DNA MethylationChild and Adolescent Psychosocial and Emotional Development

Cited by 118