Carling, David

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma

Nijhuis, A., Sikka, A., Yogev, O., Herendi, L., Balcells, C., Ma, Y., Poon, E., Eckold, C., Valbuena, G. N., Xu, Y., et al. (2022) · Nature Communications

Neuroblastoma Research and TreatmentsProtein Degradation and Inhibitors

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AMP-Activated Protein Kinase Phosphorylates Cardiac Troponin I and Alters Contractility of Murine Ventricular Myocytes

Oliveira, S. M., Zhang, Y.-H., Solis, R. S., Isackson, H., Bellahcene, M., Yavari, A., Pinter, K., Davies, J. K., Ge, Y., Ashrafian, H., et al. (2012) · Circulation Research

Cardiomyopathy and Myosin StudiesMetabolism, Diabetes, and Cancer

Cited by 86

IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells

Widjaja, A. A., Viswanathan, S., Wei Ting, J. G., Tan, J., Shekeran, S. G., Carling, D., Lim, W.-W., & Cook, S. A. (2022) · iScience

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss

Hope, D. C. D., Hinds, C. E., Lopes, T., Vincent, M. L., Shrewsbury, J. V., Yu, A. T. C., Davies, I., Scott, R., Jones, B., Murphy, K. G., et al. (2022) · Cell Reports Medicine

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

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