Ding, Sheng

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

Chang, J., Wang, Y., Shao, L., Laberge, R.-M., Demaria, M., Campisi, J., Janakiraman, K., Sharpless, N. E., Ding, S., Feng, W., et al. (2016) · Nature Medicine

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

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Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

Zhou, H., Wu, S., Joo, J. Y., Zhu, S., Han, D. W., Lin, T., Trauger, S., Bien, G., Yao, S., Zhu, Y., et al. (2009) · Cell stem cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

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Small molecules enhance CRISPR genome editing in pluripotent stem cells

Yu, C., Liu, Y., Ma, T., Liu, K., Xu, S., Zhang, Y., Liu, H., La Russa, M., Xie, M., Ding, S., et al. (2015) · Cell stem cell

CRISPR and Genetic EngineeringRNA regulation and disease

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Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

Wang, C., Ward, M. E., Chen, R., Liu, K., Tracy, T. E., Chen, X., Xie, M., Sohn, P. D., Ludwig, C., Meyer-Franke, A., et al. (2017) · Stem Cell Reports

Pluripotent Stem Cells ResearchAlzheimer's disease research and treatments

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Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism

Xu, T., Stewart, K. M., Wang, X., Liu, K., Xie, M., Ryu, J. K., Li, K., Ma, T., Wang, H., Ni, L., et al. (2017) · Nature

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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Translational strategies and challenges in regenerative medicine

Dimmeler, S., Ding, S., Rando, T. A., & Trounson, A. (2014) · Nature Medicine

Tissue Engineering and Regenerative MedicinePluripotent Stem Cells Research

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A Small‐Molecule Agonist of the Wnt Signaling Pathway

Liu, J., Wu, X., Mitchell, B., Kintner, C., Ding, S., & Schultz, P. G. (2005) · Angewandte Chemie International Edition

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

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Induction of mouse totipotent stem cells by a defined chemical cocktail.

Hu, Y., Yang, Y., Tan, P., Zhang, Y., Han, M., Yu, J., Zhang, X., Jia, Z., Wang, D., Yao, K., et al. (2023) · Nature

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

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Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease

Theodoris, C. V., Zhou, P., Liu, L., Zhang, Y., Nishino, T., Huang, Y., Kostina, A., Ranade, S. S., Gifford, C. A., Uspenskiy, V., et al. (2021) · Science

Computational Drug Discovery MethodsGene Regulatory Network Analysis

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Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia

Telpoukhovskaia, M. A., Liu, K., Sayed, F. A., Etchegaray, J. I., Xie, M., Zhan, L., Li, Y., Zhou, Y., Le, D., Bahr, B. A., et al. (2020) · Scientific Reports

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

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