Cline, Gary W.

Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes.

Krssak, M., Brehm, A., Bernroider, E., Anderwald, C., Nowotny, P., Man, C. D., Cobelli, C., Cline, G. W., Shulman, G. I., Waldhäusl, W., et al. (2004) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 313

Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance

Zhang, D., Liu, Z.-X., Choi, C. S., Tian, L., Kibbey, R., Dong, J., Cline, G. W., Wood, P. A., & Shulman, G. I. (2007) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerLiver Disease Diagnosis and Treatment

Cited by 291

Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

Choi, C. S., Befroy, D. E., Codella, R., Kim, S., Reznick, R. M., Hwang, Y.-J., Liu, Z.-X., Lee, H.-Y., Distefano, A., Samuel, V. T., et al. (2008) · Proceedings of the National Academy of Sciences

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 279

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

Neschen, S., Morino, K., Hammond, L. E., Zhang, D., Liu, Z.-X., Romanelli, A. J., Cline, G. W., Pongratz, R. L., Zhang, X.-M., Choi, C. S., et al. (2005) · Cell Metabolism

Liver Disease Diagnosis and TreatmentLipid metabolism and biosynthesis

Cited by 261

Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects.

Taylor, R., Magnusson, I., Rothman, D. L., Cline, G. W., Caumo, A., Cobelli, C., & Shulman, G. I. (1996) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerDiet, Metabolism, and Disease

Cited by 258

Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids

Vatner, D. F., Majumdar, S. K., Kumashiro, N., Petersen, M. C., Rahimi, Y., Gattu, A. K., Bears, M., Camporez, J.-P. G., Cline, G. W., Jurczak, M. J., et al. (2015) · Proceedings of the National Academy of Sciences

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 235

Effects of a Novel Glycogen Synthase Kinase-3 Inhibitor on Insulin-Stimulated Glucose Metabolism in Zucker Diabetic Fatty (fa/fa) Rats

Cline, G. W., Johnson, K., Regittnig, W., Perret, P., Tozzo, E., Xiao, L., Damico, C., & Shulman, G. I. (2002) · Diabetes

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 228

Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis

Perry, R. J., Zhang, D., Guerra, M. T., Brill, A. L., Goedeke, L., Nasiri, A. R., Rabin-Court, A., Wang, Y., Peng, L., Dufour, S., et al. (2020) · Nature

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 186

Effect of a Sustained Reduction in Plasma Free Fatty Acid Concentration on Intramuscular Long-Chain Fatty Acyl-CoAs and Insulin Action in Type 2 Diabetic Patients

Bajaj, M., Suraamornkul, S., Romanelli, A., Cline, G. W., Mandarino, L. J., Shulman, G. I., & DeFronzo, R. A. (2005) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsMetabolism, Diabetes, and Cancer

Cited by 181

Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle

Lebon, V., Dufour, S., Petersen, K. F., Ren, J., Jucker, B. M., Slezak, L. A., Cline, G. W., Rothman, D. L., & Shulman, G. I. (2001) · Journal of Clinical Investigation

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 174

Regulation of hypothalamic malonyl-CoA by central glucose and leptin

Wolfgang, M. J., Cha, S. H., Sidhaye, A., Chohnan, S., Cline, G., Shulman, G. I., & Lane, M. D. (2007) · Proceedings of the National Academy of Sciences

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 127

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

Olson, D. P., Pulinilkunnil, T., Cline, G. W., Shulman, G. I., & Lowell, B. B. (2010) · Proceedings of the National Academy of Sciences

Cancer, Lipids, and MetabolismRegulation of Appetite and Obesity

Cited by 109

Altered brain response to drinking glucose and fructose in obese adolescents

Jastreboff, A. M., Sinha, R., Arora, J., Giannini, C., Kubat, J., Malik, S., Van Name, M. A., Santoro, N., Savoye, M., Duran, E. J., et al. (2016) · Diabetes

Regulation of Appetite and ObesityNeural and Behavioral Psychology Studies

Cited by 97

Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease

ter Horst, K. W., Vatner, D. F., Zhang, D., Cline, G. W., Ackermans, M. T., Nederveen, A. J., Verheij, J., Demirkiran, A., van Wagensveld, B. A., Dallinga-Thie, G. M., et al. (2021) · Diabetes Care

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 88

The aminolysis of N-hydroxysuccinimide esters. A structure-reactivity study

Cline, G. W., & Hanna, S. B. (1987) · Journal of the American Chemical Society

Physical Organic Chemistry and Reaction KineticsChemical Synthesis and Reactions

Cited by 85

Propionate increases hepatic pyruvate cycling and anaplerosis and alters mitochondrial metabolism

Perry, R. J., Borders, C. B., Cline, G. W., Zhang, X.-M., Alves, T. C., Petersen, K. F., Rothman, D. L., Kibbey, R. G., & Shulman, G. I. (2016) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerMetabolomics and Mass Spectrometry Studies

Cited by 78

Anti-inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid-induced insulin resistance

Camporez, J. P., Lyu, K., Goldberg, E. L., Zhang, D., Cline, G. W., Jurczak, M. J., Dixit, V. D., Petersen, K. F., & Shulman, G. I. (2019) · The Journal of Physiology

Adipokines, Inflammation, and Metabolic DiseasesEstrogen and related hormone effects

Cited by 71

Glycerol-3-Phosphate Acyltransferase 1 Deficiency in ob/ob Mice Diminishes Hepatic Steatosis but Does Not Protect Against Insulin Resistance or Obesity

Wendel, A. A., Li, L. O., Li, Y., Cline, G. W., Shulman, G. I., & Coleman, R. A. (2010) · Diabetes

Liver Disease Diagnosis and TreatmentLipid metabolism and biosynthesis

Cited by 63