Kubera, Marta

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression

Maes, M., Yirmyia, R., Noraberg, J., Brene, S., Hibbeln, J., Perini, G., Kubera, M., Bob, P., Lerer, B., & Maj, M. (2009) · Metabolic Brain Disease

Tryptophan and brain disordersTreatment of Major Depression

Cited by 894

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

Maes, M., Leonard, B. E., Myint, A. M., Kubera, M., & Verkerk, R. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 700

Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut

Maes, M., Kubera, M., Leunis, J.-C., & Berk, M. (2012) · Journal of Affective Disorders

Tryptophan and brain disordersGut microbiota and health

Cited by 446

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

Kubera, M., Obuchowicz, E., Goehler, L., Brzeszcz, J., & Maes, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 443

Anti-Inflammatory Effects of Antidepressants Through Suppression of the Interferon-γ/Interleukin-10 Production Ratio

Kubera, M., Lin, A.-H., Kenis, G., Bosmans, E., van Bockstaele, D., & Maes, M. (2001) · Journal of Clinical Psychopharmacology

Tryptophan and brain disordersTreatment of Major Depression

Cited by 343

The role of zinc in neurodegenerative inflammatory pathways in depression

Szewczyk, B., Kubera, M., & Nowak, G. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Trace Elements in HealthTryptophan and brain disorders

Cited by 176

Targeting classical IL-6 signalling or IL-6 trans-signalling in depression?

Maes, M., Anderson, G., Kubera, M., & Berk, M. (2014) · Expert Opinion on Therapeutic Targets

Tryptophan and brain disordersTreatment of Major Depression

Cited by 140

Stimulatory effect of antidepressants on the production of IL-6

Kubera, M., Kenis, G., Bosmans, E., Kajta, M., Basta-Kaim, A., Scharpe, S., Budziszewska, B., & Maes, M. (2004) · International Immunopharmacology

Tryptophan and brain disordersTreatment of Major Depression

Cited by 126

Increased autoimmune activity against 5-HT: A key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression

Maes, M., Ringel, K., Kubera, M., Berk, M., & Rybakowski, J. (2012) · Journal of Affective Disorders

Tryptophan and brain disordersTreatment of Major Depression

Cited by 116

Prolonged Desipramine Treatment Increases the Production of Interleukin-10, an Anti-Inflammatory Cytokine, in C57BL/6 Mice Subjected to the Chronic Mild Stress Model of Depression

Kubera, M., Maes, M., Holan, V., Basta-Kaim, A., Roman, A., & Shani, J. (2001) · Journal of Affective Disorders

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 103

Possible contribution of IGF-1 to depressive disorder

Szczęsny, E., Ślusarczyk, J., Głombik, K., Budziszewska, B., Kubera, M., Lasoń, W., & Basta-Kaim, A. (2013) · Pharmacological Reports

Treatment of Major DepressionTryptophan and brain disorders

Cited by 68

IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) than in major depression

Maes, M., Mihaylova, I., Kubera, M., Leunis, J.-C., Twisk, F. N. M., & Geffard, M. (2012) · Metabolic Brain Disease

Fibromyalgia and Chronic Fatigue Syndrome ResearchLong-Term Effects of COVID-19

Cited by 52