Karthaus, Wouter R.

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

Gao, D., Vela, I., Sboner, A., Iaquinta, P. J., Karthaus, W. R., Gopalan, A., Dowling, C., Wanjala, J. N., Undvall, E. A., Arora, V. K., et al. (2014) · Cell

Prostate Cancer Treatment and ResearchCancer Genomics and Diagnostics

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Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex

Li, V. S. W., Ng, S. S., Boersema, P. J., Low, T. Y., Karthaus, W. R., Gerlach, J. P., Mohammed, S., Heck, A. J. R., Maurice, M. M., Mahmoudi, T., et al. (2012) · Cell

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

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A rectal cancer organoid platform to study individual responses to chemoradiation

Ganesh, K., Wu, C., O’Rourke, K. P., Szeglin, B. C., Zheng, Y., Sauvé, C.-E. G., Adileh, M., Wasserman, I., Marco, M. R., Kim, A. S., et al. (2019) · Nature Medicine

Cancer Cells and MetastasisColorectal Cancer Surgical Treatments

Cited by 569

Controlled gene expression in primary Lgr5 organoid cultures

Koo, B.-K., Stange, D. E., Sato, T., Karthaus, W., Farin, H. F., Huch, M., van Es, J. H., & Clevers, H. (2012) · Nature Methods

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 320

Reg4 + deep crypt secretory cells function as epithelial niche for Lgr5 + stem cells in colon

Sasaki, N., Sachs, N., Wiebrands, K., Ellenbroek, S. I. J., Fumagalli, A., Lyubimova, A., Begthel, H., van den Born, M., van Es, J. H., Karthaus, W. R., et al. (2016) · Proceedings of the National Academy of Sciences

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

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FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer

Arruabarrena-Aristorena, A., Maag, J. L. V., Kittane, S., Cai, Y., Karthaus, W. R., Ladewig, E., Park, J., Kannan, S., Ferrando, L., Cocco, E., et al. (2020) · Cancer Cell

Estrogen and related hormone effectsChromatin Remodeling and Cancer

Cited by 130

Allosteric interactions prime androgen receptor dimerization and activation

Wasmuth, E. V., Broeck, A. V., LaClair, J. R., Hoover, E. A., Lawrence, K. E., Paknejad, N., Pappas, K., Matthies, D., Wang, B., Feng, W., et al. (2022) · Molecular Cell

Prostate Cancer Treatment and ResearchProtein Structure and Dynamics

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