Shun, Ming-Chieh

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

Shun, M.-C., Raghavendra, N. K., Vandegraaff, N., Daigle, J. E., Hughes, S., Kellam, P., Cherepanov, P., & Engelman, A. (2007) · Genes & Development

HIV Research and TreatmentVirus-based gene therapy research

Cited by 467

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75

Hare, S., Shun, M.-C., Gupta, S. S., Valkov, E., Engelman, A., & Cherepanov, P. (2009) · PLoS Pathogens

Virus-based gene therapy researchHIV Research and Treatment

Cited by 166

HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins

Hrecka, K., Hao, C., Shun, M.-C., Kaur, S., Swanson, S. K., Florens, L., Washburn, M. P., & Skowronski, J. (2016) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentDNA Repair Mechanisms

Cited by 80

Identification and Characterization of PWWP Domain Residues Critical for LEDGF/p75 Chromatin Binding and Human Immunodeficiency Virus Type 1 Infectivity

Shun, M.-C., Botbol, Y., Li, X., Di Nunzio, F., Daigle, J. E., Yan, N., Lieberman, J., Lavigne, M., & Engelman, A. (2008) · Journal of Virology

HIV Research and TreatmentGenomics and Chromatin Dynamics

Cited by 78

The cleavage and polyadenylation specificity factor 6 (CPSF6) subunit of the capsid-recruited pre-messenger RNA cleavage factor I (CFIm) complex mediates HIV-1 integration into genes

Rasheedi, S., Shun, M.-C., Serrao, E., Sowd, G. A., Qian, J., Hao, C., Dasgupta, T., Engelman, A. N., & Skowronski, J. (2016) · Journal of Biological Chemistry

HIV Research and TreatmentVirus-based gene therapy research

Cited by 65

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding

Serrao, E., Krishnan, L., Shun, M.-C., Li, X., Cherepanov, P., Engelman, A., & Maertens, G. N. (2014) · Nucleic Acids Research

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 59