Latz, Eicke

Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes

Steinhagen, F., Zillinger, T., Peukert, K., Fox, M., Thudium, M., Barchet, W., Putensen, C., Klinman, D., Latz, E., & Bode, C. (2018) · European Journal of Immunology

interferon and immune responsesSystemic Lupus Erythematosus Research

Cited by 112

Nucleic acid‐sensing TLR s and autoimmunity: novel insights from structural and cell biology

Pelka, K., Shibata, T., Miyake, K., & Latz, E. (2016) · Immunological Reviews

Immune Response and InflammationInflammasome and immune disorders

Cited by 110

Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury

Schneider, K. M., Elfers, C., Ghallab, A., Schneider, C. V., Galvez, E. J. C., Mohs, A., Gui, W., Candels, L. S., Wirtz, T. H., Zuehlke, S., et al. (2021) · Cellular and Molecular Gastroenterology and Hepatology

Drug-Induced Hepatotoxicity and ProtectionGut microbiota and health

Cited by 108

Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway

Jiang, S., Maphis, N. M., Binder, J., Chisholm, D., Weston, L., Duran, W., Peterson, C., Zimmerman, A., Mandell, M. A., Jett, S. D., et al. (2021) · Cell Reports

Alzheimer's disease research and treatmentsInflammasome and immune disorders

Cited by 92

Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice

Tzeng, T.-C., Hasegawa, Y., Iguchi, R., Cheung, A., Caffrey, D. R., Thatcher, E. J., Mao, W., Germain, G., Tamburro, N. D., Okabe, S., et al. (2018) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 67

PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment

(ADNI), A. D. N. I., Kleineidam, L., Chouraki, V., Próchnicki, T., van der Lee, S. J., Madrid-Márquez, L., Wagner-Thelen, H., Karaca, I., Weinhold, L., Wolfsgruber, S., et al. (2020) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 62

Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent

Beyer, M. M. S., Lonnemann, N., Remus, A., Latz, E., Heneka, M. T., & Korte, M. (2020) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 55

Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study

Brosseron, F., Kolbe, C., Santarelli, F., Carvalho, S., Antonell, A., Castro‐Gomez, S., Tacik, P., Namasivayam, A. A., Mangone, G., Schneider, R., et al. (2020) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 47

Assessment and Quantification of Crystal-Induced Lysosomal Damage

Duewell, P., & Latz, E. (2013) · Methods in Molecular Biology

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 12