Tyshkovskiy, Alexander

Biological age is increased by stress and restored upon recovery

Poganik, J. R., Zhang, B., Baht, G. S., Tyshkovskiy, A., Deik, A., Kerepesi, C., Yim, S. H., Lu, A. T., Haghani, A., Gong, T., et al. (2023) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 246

A whole lifespan mouse multi-tissue DNA methylation clock

Meer, M. V., Podolskiy, D. I., Tyshkovskiy, A., & Gladyshev, V. N. (2018) · eLife

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 176

Identification and Application of Gene Expression Signatures Associated with Lifespan Extension

Tyshkovskiy, A., Bozaykut, P., Borodinova, A. A., Gerashchenko, M. V., Ables, G. P., Garratt, M., Khaitovich, P., Clish, C. B., Miller, R. A., & Gladyshev, V. N. (2019) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 167

Distinct longevity mechanisms across and within species and their association with aging

Tyshkovskiy, A., Ma, S., Shindyapina, A. V., Tikhonov, S., Lee, S.-G., Bozaykut, P., Castro, J. P., Seluanov, A., Schork, N. J., Gorbunova, V., et al. (2023) · Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 162

Chemically induced reprogramming to reverse cellular aging

Yang, J.-H., Petty, C. A., Dixon-McDougall, T., Lopez, M. V., Tyshkovskiy, A., Maybury-Lewis, S., Tian, X., Ibrahim, N., Chen, Z., Griffin, P. T., et al. (2023) · Aging

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 136

Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

Zhang, B., Lee, D. E., Trapp, A., Tyshkovskiy, A., Lu, A. T., Bareja, A., Kerepesi, C., McKay, L. K., Shindyapina, A. V., Dmitriev, S. E., et al. (2023) · Nature Aging

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 134

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A. A., Taherian Fard, A., Albornoz, E. A., Tyshkovskiy, A., Schwabenland, M., Chaggar, H. K., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A. A., Taherian Fard, A., Albornoz, E. A., Tyshkovskiy, A., Schwabenland, M., Chaggar, H. K., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A., Fard, A. T., Albornoz, E., Tyshkovskiy, A., Schwabenland, M., Chaggar, H., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2024) · eLife

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 33

Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity.

Kriukov, D., Khrameeva, E. E., Gladyshev, V. N., Dmitriev, S. E., & Tyshkovskiy, A. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 13

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J. E., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 2

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J. E., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2024) · eLife

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

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