Koh, Mei Yee

Passing the baton: the HIF switch

Koh, M. Y., & Powis, G. (2012) · Trends in Biochemical Sciences

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 589

The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion

Koh, M. Y., Lemos, R., Liu, X., & Powis, G. (2011) · Cancer Research

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 350

HIF-1 regulation: not so easy come, easy go

Koh, M. Y., Spivak-Kroizman, T. R., & Powis, G. (2008) · Trends in Biochemical Sciences

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 339

Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1α

Koh, M. Y., Spivak-Kroizman, T., Venturini, S., Welsh, S., Williams, R. R., Kirkpatrick, D. L., & Powis, G. (2008) · Molecular Cancer Therapeutics

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 309

Revisiting the HIF switch in the tumor and its immune microenvironment.

Cowman, S. J., & Koh, M. Y. (2022) · Trends in Cancer

Cancer, Hypoxia, and MetabolismCancer Immunotherapy and Biomarkers

Cited by 256

Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer

Cowman, S. J., Fuja, D. G., Liu, X.-D., Tidwell, R. S. S., Kandula, N., Sirohi, D., Agarwal, A. M., Emerson, L. L., Tripp, S. R., Mohlman, J. S., et al. (2020) · Clinical Cancer Research

Renal cell carcinoma treatmentCancer, Hypoxia, and Metabolism

Cited by 76

ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma

Green, Y. S., Ferreira dos Santos, M. C., Fuja, D. G., Reichert, E. C., Campos, A. R., Cowman, S. J., Acuña Pilarte, K., Kohan, J., Tripp, S. R., Leibold, E. A., et al. (2022) · Oncogene

Ferroptosis and cancer prognosisCancer, Hypoxia, and Metabolism

Cited by 69

The HIF Axes in Cancer - Angiogenesis, Metabolism and Immune-Modulation

Acuña-Pilarte, K., & Koh, M. Y. (2025) · Trends in Biochemical Sciences

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 64

Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis

Griffiths, G. J., Koh, M. Y., Brunton, V. G., Cawthorne, C., Reeves, N. A., Greaves, M., Tilby, M. J., Pearson, D. G., Ottley, C. J., Workman, P., et al. (2004) · Journal of Biological Chemistry

Cell death mechanisms and regulationCancer Mechanisms and Therapy

Cited by 60

Seeing the forest for the trees – single-cell atlases link CD8+ T cells and macrophages to disease progression and treatment response in kidney cancer

Koh, M. Y., Sayegh, N., & Agarwal, N. (2021) · Cancer Cell

Cancer Immunotherapy and BiomarkersRenal cell carcinoma treatment

Cited by 28