Yamamoto, Keith R.

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

Luisi, B. F., Xu, W. X., Otwinowski, Z., Freedman, L. P., Yamamoto, K. R., & Sigler, P. B. (1991) · Nature

Protein Structure and DynamicsEstrogen and related hormone effects

Cited by 1,503

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Woodruff, P. G., Boushey, H. A., Dolganov, G. M., Barker, C. S., Yang, Y. H., Donnelly, S., Ellwanger, A., Sidhu, S. S., Dao-Pick, T. P., Pantoja, C., et al. (2007) · Proceedings of the National Academy of Sciences

Asthma and respiratory diseasesAllergic Rhinitis and Sensitization

Cited by 828

Reduced levels of hsp90 compromise steroid receptor action in vivo

Picard, D., Khursheed, B., Garabedian, M. J., Fortin, M. G., Lindquist, S., & Yamamoto, K. R. (1990) · Nature

Heat shock proteins researchEstrogen and related hormone effects

Cited by 787

A prudent path forward for genomic engineering and germline gene modification

Baltimore, D., Berg, P., Botchan, M., Carroll, D., Charo, R. A., Church, G., Corn, J. E., Daley, G. Q., Doudna, J. A., Fenner, M., et al. (2015) · Science

CRISPR and Genetic EngineeringBiomedical Ethics and Regulation

Cited by 733

DNA binding site sequence directs glucocorticoid receptor structure and activity

Meijsing, S. H., Pufall, M. A., So, A. Y., Bates, D. L., Chen, L., & Yamamoto, K. R. (2009) · Science

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 673

The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

Nissen, R. M., & Yamamoto, K. R. (2000) · Genes & Development

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 559

Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Weikum, E. R., Knuesel, M. T., Ortlund, E. A., & Yamamoto, K. R. (2017) · Nature Reviews Molecular Cell Biology

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 533

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

So, A. Y.-L., Bernal, T. U., Pillsbury, M. L., Yamamoto, K. R., & Feldman, B. J. (2009) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninEstrogen and related hormone effects

Cited by 431

Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones

Freeman, B. C., & Yamamoto, K. R. (2002) · Science

Heat shock proteins researchGenomics and Chromatin Dynamics

Cited by 400

Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

Beck, I. M. E., Vanden Berghe, W., Vermeulen, L., Yamamoto, K. R., Haegeman, G., & De Bosscher, K. (2009) · Endocrine Reviews

Estrogen and related hormone effectsAdrenal Hormones and Disorders

Cited by 298

Isolation of Hsp90 mutants by screening for decreased steroid receptor function.

Bohen, S. P., & Yamamoto, K. R. (1993) · Proceedings of the National Academy of Sciences

Heat shock proteins researchFungal and yeast genetics research

Cited by 195

Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates.

Ucker, D. S., & Yamamoto, K. R. (1984) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsEstrogen and related hormone effects

Cited by 190

The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies

Freeman, B. C., Felts, S. J., Toft, D. O., & Yamamoto, K. R. (2000) · Genes & Development

Heat shock proteins researchEstrogen and related hormone effects

Cited by 168

Mutations in the glucocorticoid receptor DNA-binding domain mimic an allosteric effect of DNA 1 1Edited by P. E. Wright

van Tilborg, M. A. A., Lefstin, J. A., Kruiskamp, M., Teuben, J.-M., Boelens, R., Yamamoto, K. R., & Kaptein, R. (2000) · Journal of Molecular Biology

Protein Structure and DynamicsEstrogen and related hormone effects

Cited by 46