Boerries, Melanie

Spatially confined sub-tumor microenvironments in pancreatic cancer

Grünwald, B. T., Devisme, A., Andrieux, G., Vyas, F., Aliar, K., McCloskey, C. W., Macklin, A., Jang, G. H., Denroche, R., Romero, J. M., et al. (2021) · Cell

Pancreatic and Hepatic Oncology ResearchSingle-cell and spatial transcriptomics

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HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice

Hoefflin, R., Harlander, S., Schäfer, S., Metzger, P., Kuo, F., Schönenberger, D., Adlesic, M., Peighambari, A., Seidel, P., Chen, C.-Y., et al. (2020) · Nature Communications

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

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Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

Horak, P., Heining, C., Kreutzfeldt, S., Hutter, B., Mock, A., Hüllein, J., Fröhlich, M., Uhrig, S., Jahn, A., Rump, A., et al. (2021) · Cancer Discovery

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

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Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

Boerries, M., Grahammer, F., Eiselein, S., Buck, M., Meyer, C., Goedel, M., Bechtel, W., Zschiedrich, S., Pfeifer, D., Laloë, D., et al. (2013) · Kidney International

Renal Diseases and GlomerulopathiesRenal and related cancers

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mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

Grahammer, F., Haenisch, N., Steinhardt, F., Sandner, L., Roerden, M., Arnold, F., Cordts, T., Wanner, N., Reichardt, W., Kerjaschki, D., et al. (2014) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

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A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes

Rinschen, M. M., Gödel, M., Grahammer, F., Zschiedrich, S., Helmstädter, M., Kretz, O., Zarei, M., Braun, D. A., Dittrich, S., Pahmeyer, C., et al. (2018) · Cell Reports

Renal Diseases and GlomerulopathiesAdvanced Proteomics Techniques and Applications

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Basophils balance healing after myocardial infarction via IL-4/IL-13

Sicklinger, F., Meyer, I. S., Li, X., Radtke, D., Dicks, S., Kornadt, M. P., Mertens, C., Meier, J. K., Lavine, K. J., Zhang, Y., et al. (2021) · Journal of Clinical Investigation

Cardiac Fibrosis and RemodelingMast cells and histamine

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BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

Reischmann, N., Andrieux, G., Griffin, R., Reinheckel, T., Boerries, M., & Brummer, T. (2020) · Oncogene

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

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Improved Quantification of Circulating Tumor DNA in Translocation‐Associated Myxoid Liposarcoma by Simultaneous Detection of Breakpoints and Single Nucleotide Variants

Schmid, A., Lausch, U., Runkel, A., Kiefer, J., Pauli, T., Boerries, M., Bogner, B., Eisenhardt, S. U., & Braig, D. (2025) · Cancer Medicine

Cancer Genomics and DiagnosticsSarcoma Diagnosis and Treatment

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