Nukina, Nobuyuki

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

Iwatsubo, T., Odaka, A., Suzuki, N., Mizusawa, H., Nukina, N., & Ihara, Y. (1994) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,774

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

Urushitani, M., Sik, A., Sakurai, T., Nukina, N., Takahashi, R., & Julien, J.-P. (2006) · Nature Neuroscience

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 419

Association of γ-Secretase with Lipid Rafts in Post-Golgi and Endosome Membranes

Vetrivel, K. S., Cheng, H., Lin, W., Sakurai, T., Li, T., Nukina, N., Wong, P. C., Xu, H., & Thinakaran, G. (2004) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsLipid Membrane Structure and Behavior

Cited by 413

TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation

Matsumoto, G., Shimogori, T., Hattori, N., & Nukina, N. (2015) · Human Molecular Genetics

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 317

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

Bauer, P. O., Goswami, A., Wong, H. K., Okuno, M., Kurosawa, M., Yamada, M., Miyazaki, H., Matsumoto, G., Kino, Y., Nagai, Y., et al. (2010) · Nature Biotechnology

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 280

Crystal Structure of an Active Form of BACE1, an Enzyme Responsible for Amyloid β Protein Production

Shimizu, H., Tosaki, A., Kaneko, K., Hisano, T., Sakurai, T., & Nukina, N. (2008) · Molecular and Cellular Biology

Alzheimer's disease research and treatmentsEnzyme Structure and Function

Cited by 205

The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies

Bauer, P. O., & Nukina, N. (2009) · Journal of Neurochemistry

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

Cited by 178

Inhibition of Rho kinases enhances the degradation of mutant huntingtin

Bauer, P. O., Wong, H. K., Oyama, F., Goswami, A., Okuno, M., Kino, Y., Miyazaki, H., & Nukina, N. (2009) · Journal of Biological Chemistry

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

Cited by 102

Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice

Kurosawa, M., Matsumoto, G., Kino, Y., Okuno, M., Kurosawa-Yamada, M., Washizu, C., Taniguchi, H., Nakaso, K., Yanagawa, T., Warabi, E., et al. (2015) · Human Molecular Genetics

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 63

APOE ε3/ε4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer’s disease diagnosis

Fukumoto, H., Ingelsson, M., Gårevik, N., Wahlund, L.-O., Nukina, N., Yaguchi, Y., Shibata, M., Hyman, B. T., Rebeck, G. W., & Irizarry, M. C. (2003) · Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein E.

Kitamura, H. W., Hamanaka, H., Watanabe, M., Wada, K., Yamazaki, C., Fujita, S. C., Manabe, T., & Nukina, N. (2004) · Neuroscience Letters

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 35

Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy

Bauer, P. O., & Nukina, N. (2009) · Autophagy

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 32