Reidling, Jack C

Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice

The HD iPSC Consortium, Lim, R. G., Salazar, L. L., Wilton, D. K., King, A. R., Stocksdale, J. T., Sharifabad, D., Lau, A. L., Stevens, B., Reidling, J. C., et al. (2017) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

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Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease

Crapser, J. D., Ochaba, J., Soni, N., Reidling, J. C., Thompson, L. M., & Green, K. N. (2020) · Brain

Neuroinflammation and Neurodegeneration MechanismsGenetic Neurodegenerative Diseases

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PIAS1 regulates mutant Huntingtin accumulation and Huntington’s disease-associated phenotypes in vivo

Ochaba, J., Monteys, A. M., O’Rourke, J. G., Reidling, J. C., Steffan, J. S., Davidson, B. L., & Thompson, L. M. (2016) · Neuron

Genetic Neurodegenerative DiseasesLysosomal Storage Disorders Research

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Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation

Lim, R. G., Al-Dalahmah, O., Wu, J., Gold, M. P., Reidling, J. C., Tang, G., Adam, M., Dansu, D. K., Park, H.-J., Casaccia, P., et al. (2022) · Nature Communications

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Aberrant splicing in Huntington’s disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification

Nguyen, T. B., Miramontes, R., Chillon-Marinas, C., Maimon, R., Vazquez-Sanchez, S., Lau, A. L., McClure, N. R., England, W. E., Singha, M., Stocksdale, J. T., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Genetic Neurodegenerative DiseasesRNA Research and Splicing

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