Sankowski, Roman

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

Masuda, T., Sankowski, R., Staszewski, O., Böttcher, C., Amann, L., Sagar, Scheiwe, C., Nessler, S., Kunz, P., van Loo, G., et al. (2019) · Nature

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 1,310

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation

Jordão, M. J. C., Sankowski, R., Brendecke, S. M., Sagar, Locatelli, G., Tai, Y.-H., Tay, T. L., Schramm, E., Armbruster, S., Hagemeyer, N., et al. (2019) · Science

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 843

Microglia Heterogeneity in the Single-Cell Era

Masuda, T., Sankowski, R., Staszewski, O., & Prinz, M. (2020) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 784

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Olah, M., Menon, V., Habib, N., Taga, M. F., Ma, Y., Yung, C. J., Cimpean, M., Khairallah, A., Coronas-Samano, G., Sankowski, R., et al. (2020) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 722

Mapping microglia states in the human brain through the integration of high-dimensional techniques

Sankowski, R., Böttcher, C., Masuda, T., Geirsdottir, L., Sagar, Sindram, E., Seredenina, T., Muhs, A., Scheiwe, C., Shah, M. J., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 449

Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

Henrik Heiland, D., Ravi, V. M., Behringer, S. P., Frenking, J. H., Wurm, J., Joseph, K., Garrelfs, N. W. C., Strähle, J., Heynckes, S., Grauvogel, J., et al. (2019) · Nature Communications

Glioma Diagnosis and TreatmentNeuroinflammation and Neurodegeneration Mechanisms

Cited by 437

Resveratrol Mitigates Lipopolysaccharide- and Aβ-Mediated Microglial Inflammation by Inhibiting the TLR4/NF-Κb/STAT Signaling cascade

Capiralla, H., Vingtdeux, V., Zhao, H., Sankowski, R., Al‐Abed, Y., Davies, P., & Marambaud, P. (2012) · Journal of Neurochemistry

Neuroinflammation and Neurodegeneration MechanismsSirtuins and Resveratrol in Medicine

Cited by 426

Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration

Sankowski, R., Mader, S., & Valdés-Ferrer, S. I. (2015) · Frontiers in Cellular Neuroscience

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 351

Novel Hexb-based tools for studying microglia in the CNS

Masuda, T., Amann, L., Sankowski, R., Staszewski, O., Lenz, M., d´Errico, P., Snaidero, N., Costa Jordão, M. J., Böttcher, C., Kierdorf, K., et al. (2020) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 317

Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis

Berghoff, S. A., Spieth, L., Sun, T., Hosang, L., Schlaphoff, L., Depp, C., Düking, T., Winchenbach, J., Neuber, J., Ewers, D., et al. (2021) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 307

Specification of CNS macrophage subsets occurs postnatally in defined niches

Masuda, T., Amann, L., Monaco, G., Sankowski, R., Staszewski, O., Krueger, M., Del Gaudio, F., He, L., Paterson, N., Nent, E., et al. (2022) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 294

Multiomic spatial landscape of innate immune cells at human central nervous system borders

Sankowski, R., Süß, P., Benkendorff, A., Böttcher, C., Fernandez-Zapata, C., Chhatbar, C., Cahueau, J., Monaco, G., Gasull, A. D., Khavaran, A., et al. (2024) · Nature Medicine

Single-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 156

Key role of MIF-related neuroinflammation in neurodegeneration and cognitive impairment in Alzheimer’s disease

Nasiri, E., Sankowski, R., Dietrich, H., Oikonomidi, A., Huerta, P. T., Popp, J., Al-Abed, Y., & Bacher, M. (2020) · Molecular Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 91

GPCRomics of homeostatic and disease-associated human microglia

Hsiao, C.-C., Sankowski, R., Prinz, M., Smolders, J., Huitinga, I., & Hamann, J. (2021) · Frontiers in Immunology

Neuroinflammation and Neurodegeneration MechanismsReceptor Mechanisms and Signaling

Cited by 59

Commensal microbiota divergently affect myeloid subsets in the mammalian central nervous system during homeostasis and disease

Sankowski, R., Ahmari, J., Mezö, C., Hrabě de Angelis, A. L., Fuchs, V., Utermöhlen, O., Buch, T., Blank, T., Gomez de Agüero, M., Macpherson, A. J., et al. (2021) · The EMBO Journal

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 32

Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

Masuda, T., Sankowski, R., Staszewski, O., Böttcher, C., Amann, L., Sagar, Scheiwe, C., Nessler, S., Kunz, P., van Loo, G., et al. (2019) · Nature

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 26

Advances in understanding the immunity of the brain and its borders: Focus on brain macrophages

Süß, P., Diebold, M., & Sankowski, R. (2024) · Clinical and Translational Medicine

Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancer

Cited by 5