Guo, Jessie Yanxiang

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

Guo, J. Y., Chen, H.-Y., Mathew, R., Fan, J., Strohecker, A. M., Karsli-Uzunbas, G., Kamphorst, J. J., Chen, G., Lemons, J. M. S., Karantza, V., et al. (2011) · Genes & Development

Autophagy in Disease and TherapyCancer, Hypoxia, and Metabolism

Cited by 1,323

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

Guo, J. Y., Karsli-Uzunbas, G., Mathew, R., Aisner, S. C., Kamphorst, J. J., Strohecker, A. M., Chen, G., Price, S., Lu, W., Teng, X., et al. (2013) · Genes & Development

Autophagy in Disease and TherapyCancer, Lipids, and Metabolism

Cited by 589

Autophagy is required for glucose homeostasis and lung tumor maintenance

Karsli-Uzunbas, G., Guo, J. Y., Price, S., Teng, X., Laddha, S. V., Khor, S., Kalaany, N. Y., Jacks, T., Chan, C. S., Rabinowitz, J. D., et al. (2014) · Cancer Discovery

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 560

Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of Braf V600E–Driven Lung Tumors

Strohecker, A. M., Guo, J. Y., Karsli-Uzunbas, G., Price, S. M., Chen, G. J., Mathew, R., McMahon, M., & White, E. (2013) · Cancer Discovery

Autophagy in Disease and TherapyCancer, Hypoxia, and Metabolism

Cited by 435

Slow TCA flux and ATP production in primary solid tumours but not metastases

Bartman, C. R., Weilandt, D. R., Shen, Y., Lee, W. D., Han, Y., TeSlaa, T., Jankowski, C. S. R., Samarah, L., Park, N. R., da Silva-Diz, V., et al. (2023) · Nature

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 299

Glutamine anabolism plays a critical role in pancreatic cancer by coupling carbon and nitrogen metabolism

Bott, A. J., Shen, J., Tonelli, C., Zhan, L., Sivaram, N., Jiang, Y.-P., Yu, X., Bhatt, V., Chiles, E., Zhong, H., et al. (2019) · Cell Reports

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 185

Glutamine synthetase limits β-catenin–mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1

Dai, W., Shen, J., Yan, J., Bott, A. J., Maimouni, S., Daguplo, H. Q., Wang, Y., Khayati, K., Guo, J. Y., Zhang, L., et al. (2022) · Journal of Clinical Investigation

Amino Acid Enzymes and MetabolismCancer, Hypoxia, and Metabolism

Cited by 70