Hopf, Thomas A

Protein 3D Structure Computed from Evolutionary Sequence Variation

Marks, D. S., Colwell, L. J., Sheridan, R., Hopf, T. A., Pagnani, A., Zecchina, R., & Sander, C. (2011) · PLoS ONE

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 1,144

A large-scale evaluation of computational protein function prediction

Radivojac, P., Clark, W. T., Oron, T. R., Schnoes, A. M., Wittkop, T., Sokolov, A., Graim, K., Funk, C., Verspoor, K., Ben-Hur, A., et al. (2013) · Nature Methods

Bioinformatics and Genomic NetworksMachine Learning in Bioinformatics

Cited by 1,028

Mutation effects predicted from sequence co-variation

Hopf, T. A., Ingraham, J. B., Poelwijk, F. J., Schärfe, C. P. I., Springer, M., Sander, C., & Marks, D. S. (2017) · Nature Biotechnology

Genomics and Rare DiseasesEvolution and Genetic Dynamics

Cited by 775

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

Wang, D., Eraslan, B., Wieland, T., Hallström, B., Hopf, T., Zolg, D. P., Zecha, J., Asplund, A., Li, L., Meng, C., et al. (2019) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 750

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

Wang, D., Eraslan, B., Wieland, T., Hallström, B., Hopf, T., Zolg, D. P., Zecha, J., Asplund, A., Li, L.-H., Meng, C., et al. (2018) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 750

Protein structure prediction from sequence variation

Marks, D. S., Hopf, T. A., & Sander, C. (2012) · Nature Biotechnology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 622

Sequence co-evolution gives 3D contacts and structures of protein complexes

Hopf, T. A., Schärfe, C. P. I., Rodrigues, J. P. G. L. M., Green, A. G., Kohlbacher, O., Sander, C., Bonvin, A. M. J. J., & Marks, D. S. (2014) · eLife

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 515

PDBe-KB: collaboratively defining the biological context of structural data

PDBe-KB consortium, Varadi, M., Anyango, S., Armstrong, D., Berrisford, J., Choudhary, P., Deshpande, M., Nadzirin, N., Nair, S. S., Pravda, L., et al. (2022) · Nucleic Acids Research

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 82