Kosuri, Sriram

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

Mali, P., Aach, J., Stranges, P. B., Esvelt, K. M., Moosburner, M., Kosuri, S., Yang, L., & Church, G. M. (2013) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,752

Next-Generation Digital Information Storage in DNA

Church, G. M., Gao, Y., & Kosuri, S. (2012) · Science

DNA and Biological ComputingAdvanced biosensing and bioanalysis techniques

Cited by 1,441

Large-scale de novo DNA synthesis: technologies and applications

Kosuri, S., & Church, G. M. (2014) · Nature Methods

CRISPR and Genetic EngineeringDNA and Nucleic Acid Chemistry

Cited by 869

Causes and effects of N-terminal codon bias in bacterial genes

Goodman, D. B., Church, G. M., & Kosuri, S. (2013) · Science

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 573

Composability of regulatory sequences controlling transcription and translation in Escherichia coli

Kosuri, S., Goodman, D. B., Cambray, G., Mutalik, V. K., Gao, Y., Arkin, A. P., Endy, D., & Church, G. M. (2013) · Proceedings of the National Academy of Sciences

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 392

Engineering an allosteric transcription factor to respond to new ligands

Taylor, N. D., Garruss, A. S., Moretti, R., Chan, S., Arbing, M. A., Cascio, D., Rogers, J. K., Isaacs, F. J., Kosuri, S., Baker, D., et al. (2016) · Nature Methods

Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction

Cited by 328

Structural and functional characterization of G protein–coupled receptors with deep mutational scanning

Jones, E. M., Lubock, N. B., Venkatakrishnan, A., Wang, J., Tseng, A. M., Paggi, J. M., Latorraca, N. R., Cancilla, D., Satyadi, M., Davis, J. E., et al. (2020) · eLife

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research

Cited by 168

A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions

Chong, R., Insigne, K. D., Yao, D., Burghard, C. P., Wang, J., Hsiao, Y.-H. E., Jones, E. M., Goodman, D. B., Xiao, X., & Kosuri, S. (2019) · Molecular Cell

RNA Research and SplicingGenomics and Rare Diseases

Cited by 130

Author response: High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery

Howard, C. J., Abell, N. S., Osuna, B. A., Jones, E. M., Chan, L. Y., Chan, H., Artis, D. R., Asfaha, J. B., Bloom, J. S., Cooper, A. R., et al. (2025) · eLife

Receptor Mechanisms and SignalingRegulation of Appetite and Obesity

Cited by 0