Jenkins, Meredith L.

Expanding the scope of electrophiles capable of targeting K-Ras oncogenes

McGregor, L. M., Jenkins, M. L., Kerwin, C., Burke, J. E., & Shokat, K. M. (2017) · Biochemistry

Protein Kinase Regulation and GTPase SignalingClick Chemistry and Applications

Cited by 97

Recognition of protein-linked glycans as a determinant of peptidase activity

Noach, I., Ficko-Blean, E., Pluvinage, B., Stuart, C., Jenkins, M. L., Brochu, D., Buenbrazo, N., Wakarchuk, W., Burke, J. E., Gilbert, M., et al. (2017) · Proceedings of the National Academy of Sciences

Glycosylation and Glycoproteins ResearchProtease and Inhibitor Mechanisms

Cited by 89

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

Choi, Y. M., Ajjaji, D., Fleming, K. D., Borbat, P. P., Jenkins, M. L., Moeller, B. E., Fernando, S., Bhatia, S. R., Freed, J. H., Burke, J. E., et al. (2023) · Nature Communications

Lipid metabolism and biosynthesisLipid Membrane Structure and Behavior

Cited by 57

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

Choi, Y. M., Ajjaji, D., Fleming, K. D., Borbat, P. P., Jenkins, M. L., Moeller, B. E., Fernando, S., Bhatia, S. R., Freed, J. H., Burke, J. E., et al. (2022) · Nature Communications

Lipid metabolism and biosynthesisLipid Membrane Structure and Behavior

Cited by 57

Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs

Rathinaswamy, M. K., Jenkins, M. L., Duewell, B. R., Zhang, X., Harris, N. J., Evans, J. T., Stariha, J. T. B., Dalwadi, U., Fleming, K. D., Ranga-Prasad, H., et al. (2023) · Cell Reports

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 28

Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs

Rathinaswamy, M. K., Jenkins, M. L., Zhang, X., Stariha, J. T., Ranga-Prasad, H., Dalwadi, U., Fleming, K. D., Yip, C. K., Williams, R. L., & Burke, J. E. (2022) · Cell Reports

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 28

Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes

Siraliev-Perez, E., Stariha, J. T., Hoffmann, R. M., Temple, B. R., Zhang, Q., Hajicek, N., Jenkins, M. L., Burke, J. E., & Sondek, J. (2022) · eLife

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

Cited by 18

Structure of Calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A

Shaw, A. L., Suresh, S., Parson, M. A., Harris, N. J., Jenkins, M. L., Yip, C. K., & Burke, J. E. (2024) · Structure

Cellular transport and secretionSignaling Pathways in Disease

Cited by 8

Structure of calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A

Shaw, A. L., Suresh, S., Parson, M. A. H., Harris, N. J., Jenkins, M. L., Yip, C. K., & Burke, J. E. (2024) · Structure

Cellular transport and secretionSignaling Pathways in Disease

Cited by 8