Armirotti, Andrea

A catalytically silent FAAH-1 variant drives anandamide transport in neurons

Fu, J., Bottegoni, G., Sasso, O., Bertorelli, R., Rocchia, W., Masetti, M., Guijarro, A., Lodola, A., Armirotti, A., Garau, G., et al. (2012) · Nature Neuroscience

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 175

Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors

Prati, F., De Simone, A., Bisignano, P., Armirotti, A., Summa, M., Pizzirani, D., Scarpelli, R., Perez, D. I., Andrisano, V., Perez‐Castillo, A., et al. (2015) · Angewandte Chemie International Edition

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 128

Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions

Sasso, O., Bertorelli, R., Bandiera, T., Scarpelli, R., Colombano, G., Armirotti, A., Moreno-Sanz, G., Reggiani, A., & Piomelli, D. (2012) · Pharmacological Research

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 96

Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain

Brindisi, M., Maramai, S., Gemma, S., Brogi, S., Grillo, A., Di Cesare Mannelli, L., Gabellieri, E., Lamponi, S., Saponara, S., Gorelli, B., et al. (2016) · Journal of Medicinal Chemistry

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 86

Effects of peripheral FAAH blockade on NTG-induced hyperalgesia—evaluation of URB937 in an animal model of migraine

Greco, R., Bandiera, T., Mangione, A., Demartini, C., Siani, F., Nappi, G., Sandrini, G., Guijarro, A., Armirotti, A., Piomelli, D., et al. (2015) · Cephalalgia

Migraine and Headache StudiesPain Mechanisms and Treatments

Cited by 63

Synergic functions of miRNAs determine neuronal fate of adult neural stem cells

Pons-Espinal, M., de Luca, E., Marzi, M. J., Beckervordersandforth, R., Armirotti, A., Nicassio, F., Fabel, K., Kempermann, G., & De Pietri Tonelli, D. (2017) · Stem Cell Reports

Neurogenesis and neuroplasticity mechanismsMicroRNA in disease regulation

Cited by 59

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

Jahid, S., Ortega, J. A., Vuong, L. M., Acquistapace, I. M., Hachey, S. J., Flesher, J. L., La Serra, M. A., Brindani, N., La Sala, G., Manigrasso, J., et al. (2022) · Cell Reports

Protein Kinase Regulation and GTPase SignalingComputational Drug Discovery Methods

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