Fennell, Dean A.

Tracking the Evolution of Non–Small-Cell Lung Cancer

Jamal-Hanjani, M., Wilson, G. A., McGranahan, N., Birkbak, N. J., Watkins, T. B. K., Veeriah, S., Shafi, S., Johnson, D. H., Mitter, R., Rosenthal, R., et al. (2017) · New England Journal of Medicine

Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations

Cited by 2,349

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

McGranahan, N., Rosenthal, R., Hiley, C. T., Rowan, A. J., Watkins, T. B. K., Wilson, G. A., Birkbak, N. J., Veeriah, S., Van Loo, P., Herrero, J., et al. (2017) · Cell

Cancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics

Cited by 1,298

Lung adenocarcinoma promotion by air pollutants

Hill, W., Lim, E. L., Weeden, C. E., Lee, C., Augustine, M., Chen, K., Kuan, F.-C., Marongiu, F., Evans, E. J., Moore, D. A., et al. (2023) · Nature

Air Quality and Health ImpactsCarcinogens and Genotoxicity Assessment

Cited by 808

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Arce Vargas, F., Furness, A. J. S., Litchfield, K., Joshi, K., Rosenthal, R., Ghorani, E., Solomon, I., Lesko, M. H., Ruef, N., Roddie, C., et al. (2018) · Cancer Cell

Cancer Immunotherapy and BiomarkersMonoclonal and Polyclonal Antibodies Research

Cited by 592

Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer

Delage, B., Fennell, D. A., Nicholson, L., McNeish, I., Lemoine, N. R., Crook, T., & Szlosarek, P. W. (2010) · International Journal of Cancer

Bacterial Cancer TherapyAmino Acid Enzymes and Metabolism

Cited by 441

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Abbosh, C., Frankell, A. M., Harrison, T., Kisistok, J., Garnett, A., Johnson, L., Veeriah, S., Moreau, M., Chesh, A., Chaunzwa, T. L., et al. (2023) · Nature

Cancer Genomics and DiagnosticsLung Cancer Diagnosis and Treatment

Cited by 382

Novel Insights into Mesothelioma Biology and Implications for Therapy

Yap, T. A., Aerts, J. G., Popat, S., & Fennell, D. A. (2017) · Nature reviews. Cancer

Occupational and environmental lung diseasesIntraperitoneal and Appendiceal Malignancies

Cited by 324

Medical and Surgical Care of Patients with Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations

Carbone, M., Pass, H. I., Ak, G., Alexander, H. R., Baas, P., Baumann, F., Blakely, A. M., Bueno, R., Bzura, A., Cardillo, G., et al. (2022) · Journal of Thoracic Oncology

Occupational and environmental lung diseasesBRCA gene mutations in cancer

Cited by 97

Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly

Majkut, J., Sgobba, M., Holohan, C., Crawford, N., Logan, A. E., Kerr, E., Higgins, C. A., Redmond, K. L., Riley, J. S., Stasik, I., et al. (2014) · Nature Communications

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 81

Phase 2, multicenter study of the EZH2 inhibitor tazemetostat as monotherapy in adults with relapsed or refractory (R/R) malignant mesothelioma (MM) with BAP1 inactivation.

Zauderer, M. G., Szlosarek, P., Le Moulec, S., Popat, S., Taylor, P., Planchard, D., Scherpereel, A., Jahan, T., Koczywas, M., Forster, M., et al. (2018) · Journal of Clinical Oncology

Occupational and environmental lung diseasesIntraperitoneal and Appendiceal Malignancies

Cited by 54

Expression and Prognostic Significance of Hypoxia-Inducible Factor 1α (HIF-1α) in Malignant Pleural Mesothelioma (MPM)

Klabatsa, A., Sheaff, M. T., Steele, J. P. C., Evans, M. T., Rudd, R. M., & Fennell, D. A. (2006) · Lung Cancer

Occupational and environmental lung diseasesCancer, Hypoxia, and Metabolism

Cited by 53

Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma

Barbone, D., Van Dam, L., Follo, C., Jithesh, P. V., Zhang, S.-D., Richards, W. G., Bueno, R., Fennell, D. A., & Broaddus, V. C. (2016) · PLOS ONE

Occupational and environmental lung diseasesIntraperitoneal and Appendiceal Malignancies

Cited by 48

Wnt–β-catenin–Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer

Ravindranath, A., Yuen, H.-F., Chan, K.-K., Grills, C., Fennell, D. A., Lappin, T. R., & El-Tanani, M. (2011) · British Journal of Cancer

Wnt/β-catenin signaling in development and cancerBone and Dental Protein Studies

Cited by 46

PS01.11 Nivolumab Versus Placebo in Relapsed Malignant Mesothelioma: The CONFIRM Phase 3 Trial

Fennell, D., Ottensmeier, C., Califano, R., Hanna, G., Ewings, S., Hill, K., Wilding, S., Danson, S., Nye, M., Steele, N., et al. (2021) · Journal of Thoracic Oncology

Occupational and environmental lung diseasesIntraperitoneal and Appendiceal Malignancies

Cited by 34

Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature

Barr, M. P., Gray, S. G., Hoffmann, A. C., Hilger, R. A., Thomale, J., O’Flaherty, J. D., Fennell, D. A., Richard, D., O’Leary, J. J., & O’Byrne, K. J. (2013) · PLoS ONE

Cancer Cells and MetastasisMetal complexes synthesis and properties

Cited by 19

A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer

Middleton, G., Robbins, H. L., Fletcher, P., Savage, J., Mehmi, M., Summers, Y., Greystoke, A., Steele, N., Popat, S., Jain, P., et al. (2025) · npj Precision Oncology

Lung Cancer Treatments and MutationsPI3K/AKT/mTOR signaling in cancer

Cited by 7