Bartus, Raymond T.

The cholinergic hypothesis of geriatric memory dysfunction

Bartus, R. T., Dean, R. L., Beer, B., & Lippa, A. S. (1982) · Science

Cholinesterase and Neurodegenerative DiseasesDementia and Cognitive Impairment Research

Cited by 5,545

On Neurodegenerative Diseases, Models, and Treatment Strategies: Lessons Learned and Lessons Forgotten a Generation Following the Cholinergic Hypothesis

Bartus, R. T. (2000) · Experimental Neurology

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 829

Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial

Marks, W. J., Ostrem, J. L., Verhagen, L., Starr, P. A., Larson, P. S., Bakay, R. A., Taylor, R., Cahn-Weiner, D. A., Stoessl, A. J., Olanow, C. W., et al. (2008) · The Lancet Neurology

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 596

A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer’s disease

Rafii, M. S., Baumann, T. L., Bakay, R. A. E., Ostrove, J. M., Siffert, J., Fleisher, A. S., Herzog, C. D., Barba, D., Pay, M., Salmon, D. P., et al. (2014) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsVirus-based gene therapy research

Cited by 223

Profound effects of combining choline and piracetam on memory enhancement and cholinergic function in aged rats

Bartus, R. T., Dean, R. L., Sherman, K. A., Friedman, E., & Beer, B. (1981) · Neurobiology of Aging

Cholinesterase and Neurodegenerative DiseasesNeuroprotection in Cerebral Ischemia

Cited by 140

Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned?

Bartus, R. T., & Johnson, E. M. (2017) · Neurobiology of Disease

Nerve injury and regenerationAlzheimer's disease research and treatments

Cited by 97

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease

Chu, Y., Bartus, R. T., Manfredsson, F. P., Olanow, C. W., & Kordower, J. H. (2020) · Brain

Parkinson's Disease Mechanisms and TreatmentsVirus-based gene therapy research

Cited by 88

Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum

Herzog, C. D., Dass, B., Gasmi, M., Bakay, R., Stansell, J. E., Tuszynski, M., Bankiewicz, K., Chen, E.-Y., Chu, Y., Bishop, K., et al. (2008) · Molecular Therapy

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 72

Gene transfer provides a practical means for safe, long-term, targeted delivery of biologically active neurotrophic factor proteins for neurodegenerative diseases

Herzog, C. D., Bishop, K. M., Brown, L., Wilson, A., Kordower, J. H., & Bartus, R. T. (2011) · Drug Delivery and Translational Research

Virus-based gene therapy researchAlzheimer's disease research and treatments

Cited by 29