The cholinergic hypothesis of geriatric memory dysfunction

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Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey

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Human Memory and the Cholinergic System

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Human Serial Learning: Enhancement with Arecholine and Choline Impairment with Scopolamine

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NEOCORTICAL CHOLINERGIC NEURONS IN ELDERLY PEOPLE

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Changes in the Brain Catecholamines in Patients with Dementia of Alzheimer Type

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Cholinergic projections from magnocellular nuclei of the basal forebrain to cortical areas in rats

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Physostigmine: Improvement of Long-Term Memory Processes in Normal Humans

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Acetylcholinesterase-rich projections from the basal forebrain of the rhesus monkey to neocortex

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Dementia in Parkinson disease

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Memory Complaint and Impairment in the Aged

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Physostigmine and Arecoline: Effects of Intravenous Infusions in Alzheimer Presenile Dementia

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Catecholamine metabolism in the brains of ageing male mice

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Pre- and postsynaptic neurochemical alterations in Alzheimer's disease

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Brain acetylcholine: Increase after systematic choline administration

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Dementia in Parkinson disease

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Short-term memory in the rhesus monkey: Disruption from the anti-cholinergic scopolamine

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Regional distribution of muscarinic acetylcholine receptor in normal and Alzheimer's-type dementia brains

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A Quantitative Study of the Pigmented Neurons in the Nuclei Locus Coeruleus and Subcoeruleus in Man as Related to Aging

Vijayashankar, N., & Brody, H. (1979) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197909000-00004 · Cited by 301 · see citing works

Changes in the Monoamine Containing Neurones of the Human Cns in Senile Dementia

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Aging in the Rhesus Monkey: Debilitating Effects on Short-term Memory

Bartus, R. T., Fleming, D., & Johnson, H. R. (1978) · Journal of Gerontology · doi:10.1093/geronj/33.6.858 · Cited by 284 · see citing works

Age-Related Changes in Passive Avoidance Retention: Modulation with Dietary Choline

Bartus, R. T., Dean, R. L., Goas, J. A., & LIPPA, A. S. (1980) · Science · doi:10.1126/science.7384805 · Cited by 275 · see citing works

Cortical somatostatin-like immunoreactivity in cases of Alzheimer's disease and senile Dementia of the Alzheimer type

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Effects of diazepam and scopolamine on storage, retrieval and organizational processes in memory

Ghoneim, M. M., & Mewaldt, S. P. (1975) · Psychopharmacology · doi:10.1007/bf00428903 · Cited by 271 · see citing works

Impaired Learning and Decreased Cortical Norepinephrine after Bilateral Locus Coeruleus Lesions

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Evidence for Depressed Catecholamine and Enhanced Serotonin Metabolism in Aging Male Rats: Possible Relation to Gondotropin Secretion2

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THE CHOLINERGIC SYSTEM IN OLD AGE AND ALZHEIMER'S DISEASE

Perry, E. K. (1980) · Age and Ageing · doi:10.1093/ageing/9.1.1 · Cited by 248 · see citing works

Age-related alterations in the rodent brain cholinergic system and behavior

Strong, R., Hicks, P. B., Hsu, L. L., et al. (1980) · Neurobiology of Aging · doi:10.1016/0197-4580(80)90025-1 · Cited by 238 · see citing works

Coenzyme a-acetylating enzymes in Alzheimer's disease: Possible cholinergic ‘compartment’ of pyruvate dehydrogenase

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Letter: Inadequate mothers.

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Brain Acetylcholine Synthesis Declines with Senescence

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Age-related behavioral and neurobiological changes: A review with an emphasis on memory

Kubanis, P., & Zornetzer, S. F. (1981) · Behavioral and Neural Biology · doi:10.1016/s0163-1047(81)91195-x · Cited by 222 · see citing works

Energy‐Metabolising Enzymes in Brain Regions of Adult and Aging Rats

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Increase in rat brain acetylcholine induced by choline or deanol

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Age and neurochemical correlates of radial maze performance in rats

Ingram, D. K., London, E. D., & Goodrick, C. L. (1981) · Neurobiology of Aging · doi:10.1016/0197-4580(81)90058-0 · Cited by 217 · see citing works

AN ANALYSIS OF FACTORS INFLUENCING MEASUREMENTS OF DOPAMINE, NORADRENALINE, GLUTAMATEDECARBOXYLASE AND CHOLINE ACETYLASE IN HUMAN POST-MORTEM BRAIN TISSUE

Spokes, E. G. (1979) · Brain · doi:10.1093/brain/102.2.333 · Cited by 216 · see citing works

Physostigmine and Recent Memory: Effects in Young and Aged Nonhuman Primates

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Age-related differences in behavior across the life span of the C57BL/6J mouse

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GLUCOSE METABOLISM AND ACETYLCHOLINE SYNTHESIS IN RELATION TO NEURONAL ACTIVITY IN ALZHEIMER'S DISEASE

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Age-related Changes in the Nigrostriatum: A Behavioral and Biochemical Analysis

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Emanuel Miller. M.A. Cantab., F.R.C.P., D.P.M.

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Effects of physostigmine and lecithin on memory in Alzheimer disease

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Aging and brain enzymes

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Reduced dopaminergic binding during aging in the rodent striatum

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ALZHEIMER-LIKE CHOLINERGIC DEFICIENCY IN DOWN SYNDROME

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PLASMA CHOLINE: ITS TURNOVER AND EXCHANGE WITH BRAIN CHOLINE

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Evidence for a direct cholinergic involvement in the scopolamine-induced amnesia in monkeys: Effects of concurrent administration of physostigmine and methylphenidate with scopolamine

Bartus, R. T. (1978) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(78)90364-7 · Cited by 181 · see citing works

Changes in the activity and amounts of enzymes synthesizing catecholamines and acetylcholine in brain, adrenal medulla, and sympathetic ganglia of aged rat and mouse

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Neuropathological and biochemical observations on the noradrenergic system in Alzheimer's disease

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Memory Deficits in Aged Cebus Monkeys and Facilitation With Central Cholinomimetics

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A cholinergic connection between normal aging and senile dementia in the human hippocampus

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INTELLECTUAL IMPAIRMENT IN PARKINSON'S SYNDROME

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Pain Sensitivity in Schizophrenics

Davis, K. L., Mohs, R. C., & Tinklenberg, J. R. (1979) · New England Journal of Medicine · doi:10.1056/nejm197910253011722 · Cited by 159 · see citing works

FAMILIAR ABBREVIATIONS

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Physostigmine: Effects on cognition and affect in normal subjects

Davis, K. L., Hollister, L. E., Overall, J. E., et al. (1976) · Psychopharmacology · doi:10.1007/bf00426316 · Cited by 141 · see citing works

Profound effects of combining choline and piracetam on memory enhancement and cholinergic function in aged rats

Bartus, R. T., Dean, R. L., Sherman, K. A., Friedman, E., & Beer, B. (1981) · Neurobiology of Aging · doi:10.1016/0197-4580(81)90007-5 · Cited by 140 · see citing works

Presynaptic cholinergic mechanisms in brain of aged rats with memory impairments

Sherman, K. A., Kuster, J. E., Dean, R. L., Bartus, R. T., & Friedman, E. (1981) · Neurobiology of Aging · doi:10.1016/0197-4580(81)90006-3 · Cited by 139 · see citing works

Aging-induced Changes in Acetylcholine and Serotonin Content of Discrete Brain Nuclei

Meek, J. L., Bertilsson, L., Cheney, D. L., et al. (1977) · Journal of Gerontology · doi:10.1093/geronj/32.2.129 · Cited by 131 · see citing works

Reduced corticol choline acetyltransferase activity in senile dementia of Alzheimer type is not accompanied by changes in vasoactive intestinal polypeptide

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The effects and interactions of scopolamine, physostigmine and methamphetamine on human memory

Mewaldt, S. P., & Ghoneim, M. M. (1979) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(79)90088-1 · Cited by 122 · see citing works

The Delayed-Response Problem

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Ageing and dopamine uptake by subcellular fractions of the C57BL/6J male mouse brain

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The Extrapyramidal Disorder of Alzheimer’s Disease

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Physostigmine induction of depressive symptomatology in normal human subjects

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Dopamine receptor sensitivity in brain and retina of rats during aging

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Do Hippocampal Lesions Produce Amnesia in Animals?

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Lecithin Consumption Increases Acetylcholine Concentrations in Rat Brain and Adrenal Gland

Hirsch, M. J., & Wurtman, R. J. (1978) · Science · doi:10.1126/science.694529 · Cited by 108 · see citing works

Regulation of acetylcholine synthesis in nervous tissue

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Aging, memory, and the cholinergic system: A study of dichotic listening☆

Drachman, D. B., Noffsinger, D., Sahakian, B. J., Kurdziel, S. A., & FLEMING, P. (1980) · Neurobiology of Aging · doi:10.1016/0197-4580(80)90022-6 · Cited by 101 · see citing works

Changes in Learning and Memory During Aging

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Selective vulnerability of neurones in organic dementia

Spillane, J. A., White, P., Goodhardt, M., FLACK, R. H. A., Bowen, D. M., & DAVISON, A. N. (1977) · Nature · doi:10.1038/266558a0 · Cited by 100 · see citing works

Postmortem stability of α-bungarotoxin binding sites in mouse and human brain

Davies, P., & Feisullin, S. (1981) · Brain Research · doi:10.1016/0006-8993(81)90148-7 · Cited by 99 · see citing works

Memory and Cognitive Function in the Elderly

Drachman, D. A. (1980) · Archives of Neurology · doi:10.1001/archneur.1980.00500590098022 · Cited by 92 · see citing works

Evidence for selective loss of brain dopamine- and histamine-stimulated adenylate cyclase activities in rabbits with aging

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Age Changes in the Human for Some Enzymes Associated with Metabolism of Catecholamines, GABA and Acetylcholine

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Possible biochemical basis of memory disorder in Alzheimer disease

Smith, C. M., & Swash, M. (1978) · Annals of Neurology · doi:10.1002/ana.410030602 · Cited by 88 · see citing works

Hypoxia-induced amnesia in one-trial learning and pharmacological protection by piracetam

Sara, S. J., & Lefevre, D. (1972) · Psychopharmacology · doi:10.1007/bf00422614 · Cited by 88 · see citing works

Cholinergic receptor loss in brains of aging mice

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ARGININE VASOPRESSIN AND CHOLINE ACETYLTRANSFERASE IN BRAINS OF PATIENTS WITH ALZHEIMER TYPE SENILE DEMENTIA

Rossor, M. N., Iversen, L. L., Mountjoy, C. Q., Roth, M., Hawthorn, J., Ang, V., & Jenkins, J. S. (1980) · The Lancet · doi:10.1016/s0140-6736(80)92428-9 · Cited by 80 · see citing works

Age-dependent Changes in the Oxidative Metabolism in Rat Brain

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Clinical Response to Choline plus Piracetam in Senile Dementia: Relation to Red-Cell Choline Levels

Friedman, E., Sherman, K., Ferris, S. H., et al. (1981) · New England Journal of Medicine · doi:10.1056/nejm198106113042413 · Cited by 79 · see citing works

Choline: Selective enhancement of serial learning and encoding of low imagery words in man

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Normal cortical concentration of cholecystokinin-like immunoreactivity with reduced choline acetyltransferase activity in senile dementia of Alzheimer type

Rossor, M. N., Rehfeld, J. F., Emson, P. C., et al. (1981) · Life Sciences · doi:10.1016/0024-3205(81)90334-9 · Cited by 77 · see citing works

Effect of Physostigmine on Constructional and Memory Tasks in Alzheimer's Disease

Muramoto, O., Sugishita, M., SUGITA, H., et al. (1979) · Archives of Neurology · doi:10.1001/archneur.1979.00500440071014 · Cited by 77 · see citing works

Piracetam diminishes hippocampal acetylcholine levels in rats

Wurtman, R. J., Magil, S. G., & Reinstein, D. K. (1981) · Life Sciences · doi:10.1016/0024-3205(81)90685-8 · Cited by 76 · see citing works

Choline Excites Cortical Neurons

Krnjević, K., & Reinhardt, W. (1979) · Science · doi:10.1126/science.515735 · Cited by 72 · see citing works

Choline Administration: Modification of the Central Actions of Atropine

Wecker, L., Dettbarn, W., & Schmidt, D. E. (1978) · Science · doi:10.1126/science.199.4324.86 · Cited by 72 · see citing works

Alzheimer disease

Etienne, P. E., Dastoor, D., Gauthier, S. G., Ludwick, R., & Collier, B. (1981) · Neurology · doi:10.1212/wnl.31.12.1552 · Cited by 70 · see citing works

Effects of age on brain oxidative metabolism in vivo

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Neurotransmitter and carbohydrate metabolism during aging and mild hypoxia

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