Loewith, Robbie

TOR signaling in growth and metabolism

Wullschleger, S., Loewith, R., & Hall, M. N. (2006) · Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 5,787

Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control

Loewith, R., Jacinto, E., Wullschleger, S., Lorberg, A., Crespo, J. L., Bonenfant, D., Oppliger, W., Jenoe, P., & Hall, M. N. (2002) · Molecular Cell

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

Cited by 1,886

A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

Knight, Z. A., Gonzalez, B., Feldman, M. E., Zunder, E. R., Goldenberg, D. D., Williams, O., Loewith, R., Stokoe, D., Balla, A., Toth, B., et al. (2006) · Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 1,174

Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae

Urban, J., Soulard, A., Huber, A., Lippman, S., Mukhopadhyay, D., Deloche, O., Wanke, V., Anrather, D., Ammerer, G., Riezman, H., et al. (2007) · Molecular Cell

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

Cited by 798

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling

Shekhar-Guturja, T., Gunaherath, G. M. K. B., Wijeratne, E. M. K., Lambert, J.-P., Averette, A. F., Lee, S. C., Kim, T., Bahn, Y.-S., Tripodi, F., Ammar, R., et al. (2016) · Nature Chemical Biology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 101

EGOC inhibits TOROID polymerization by structurally activating TORC1

Prouteau, M., Bourgoint, C., Felix, J., Bonadei, L., Sadian, Y., Gabus, C., Savvides, S. N., Gutsche, I., Desfosses, A., & Loewith, R. (2023) · Nature Structural & Molecular Biology

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

Cited by 15

EGOC inhibits TOROID polymerization by structurally activating TORC1

Prouteau, M., Bourgoint, C., Felix, J., Bonadei, L., Sadian, Y., Gabus, C., Savvides, S., Gutsche, I., Desfosses, A., & Loewith, R. (2022) · Nature Structural & Molecular Biology

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

Cited by 15

Structure and function of the yeast amino acid-sensing SEAC–EGOC supercomplex

Tafur, L., Bonadei, L., Zheng, Y., Gabus, C., & Loewith, R. (2026) · Nature Structural & Molecular Biology

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

Cited by 4

Structure and function of the yeast amino acid-sensing SEAC-EGOC supercomplex

Tafur, L., Bonadei, L., Zheng, Y., & Loewith, R. (2024) · Nature Structural & Molecular Biology

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

Cited by 4