Patel, Sachin

Endocannabinoid Signaling Negatively Modulates Stress-Induced Activation of the Hypothalamic-Pituitary-Adrenal Axis

Patel, S., Roelke, C. T., Rademacher, D. J., Cullinan, W. E., & Hillard, C. J. (2004) · Endocrinology

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 475

Downregulation of Endocannabinoid Signaling in the Hippocampus Following Chronic Unpredictable Stress

Hill, M. N., Patel, S., Carrier, E. J., Rademacher, D. J., Ormerod, B. K., Hillard, C. J., & Gorzalka, B. B. (2005) · Neuropsychopharmacology

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 363

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

Gunduz-Cinar, O., MacPherson, K. P., Cinar, R., Gamble-George, J., Sugden, K., Williams, B., Godlewski, G., Ramikie, T. S., Gorka, A. X., Alapafuja, S. O., et al. (2013) · Molecular Psychiatry

Cannabis and Cannabinoid ResearchMemory and Neural Mechanisms

Cited by 307

Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling

Patel, S., Roelke, C. T., Rademacher, D. J., & Hillard, C. J. (2005) · European Journal of Neuroscience

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 297

Functional Interactions between Stress and the Endocannabinoid System: From Synaptic Signaling to Behavioral Output

Hill, M. N., Patel, S., Campolongo, P., Tasker, J. G., Wotjak, C. T., & Bains, J. S. (2010) · The Journal of Neuroscience

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 255

Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety

Gray, J. M., Vecchiarelli, H. A., Morena, M., Lee, T. T. Y., Hermanson, D. J., Kim, A. B., McLaughlin, R. J., Hassan, K. I., Kühne, C., Wotjak, C. T., et al. (2015) · The Journal of Neuroscience

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 246

Prefrontal inputs to the amygdala instruct fear extinction memory formation

Bukalo, O., Pinard, C. R., Silverstein, S., Brehm, C., Hartley, N. D., Whittle, N., Colacicco, G., Busch, E., Patel, S., Singewald, N., et al. (2015) · Science Advances

Memory and Neural MechanismsMemory Processes and Influences

Cited by 234

The endocannabinoid system as a target for novel anxiolytic drugs

Patel, S., Hill, M. N., Cheer, J. F., Wotjak, C. T., & Holmes, A. (2017) · Neuroscience & Biobehavioral Reviews

Cannabis and Cannabinoid ResearchMedicinal Plant Extracts Effects

Cited by 233

Strain Differences in Stress Responsivity Are Associated with Divergent Amygdala Gene Expression and Glutamate-Mediated Neuronal Excitability

Mozhui, K., Karlsson, R.-M., Kash, T. L., Ihne, J., Norcross, M., Patel, S., Farrell, M. R., Hill, E. E., Graybeal, C., Martin, K. P., et al. (2010) · The Journal of Neuroscience

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 226

Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala

Patel, S., Cravatt, B. F., & Hillard, C. J. (2005) · Neuropsychopharmacology

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 164

Adaptations in endocannabinoid signaling in response to repeated homotypic stress: a novel mechanism for stress habituation

Patel, S., & Hillard, C. J. (2008) · European Journal of Neuroscience

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 162

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

Bluett, R. J., Gamble-George, J. C., Hermanson, D. J., Hartley, N. D., Marnett, L. J., & Patel, S. (2014) · Translational Psychiatry

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 157

Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation

Shonesy, B. C., Bluett, R. J., Ramikie, T. S., Báldi, R., Hermanson, D. J., Kingsley, P. J., Marnett, L. J., Winder, D. G., Colbran, R. J., & Patel, S. (2014) · Cell Reports

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 155

Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala

Patel, S., Kingsley, P. J., Mackie, K., Marnett, L. J., & Winder, D. G. (2009) · Neuropsychopharmacology

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 153

Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation

Hermanson, D. J., Hartley, N. D., Gamble-George, J., Brown, N., Shonesy, B. C., Kingsley, P. J., Colbran, R. J., Reese, J., Marnett, L. J., & Patel, S. (2013) · Nature Neuroscience

Cannabis and Cannabinoid ResearchInflammatory mediators and NSAID effects

Cited by 126

Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation

Sumislawski, J. J., Ramikie, T. S., & Patel, S. (2011) · Neuropsychopharmacology

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

Cited by 124

An endocannabinoid-regulated basolateral amygdala–nucleus accumbens circuit modulates sociability

Folkes, O. M., Báldi, R., Kondev, V., Marcus, D. J., Hartley, N. D., Turner, B. D., Ayers, J. K., Baechle, J. J., Misra, M. P., Altemus, M., et al. (2020) · Journal of Clinical Investigation

Cannabis and Cannabinoid ResearchAutism Spectrum Disorder Research

Cited by 119

Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening

Marcus, D. J., Bedse, G., Gaulden, A. D., Ryan, J. D., Kondev, V., Winters, N. D., Rosas-Vidal, L. E., Altemus, M., Mackie, K., Lee, F. S., et al. (2020) · Neuron

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 104

Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress

Ramikie, T. S., & Patel, S. (2012) · Neuroscience

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 62

Driving the downward spiral: alcohol-induced dysregulation of extended amygdala circuits and negative affect

Centanni, S. W., Bedse, G., Patel, S., & Winder, D. G. (2019) · Alcoholism: Clinical and Experimental Research

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 58

Cyclooxygenase-2 inhibition reduces stress-induced affective pathology

Gamble-George, J. C., Baldi, R., Halladay, L., Kocharian, A., Hartley, N., Silva, C. G., Roberts, H., Haymer, A., Marnett, L. J., Holmes, A., et al. (2016) · eLife

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 55