Hetzer, Martin W.

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

Mertens, J., Paquola, A. C. M., Ku, M., Hatch, E., Böhnke, L., Ladjevardi, S., McGrath, S., Campbell, B., Lee, H., Herdy, J. R., et al. (2015) · Cell Stem Cell

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 765

Catastrophic nuclear envelope collapse in cancer cell micronuclei

Hatch, E. M., Fischer, A. H., Deerinck, T. J., & Hetzer, M. W. (2013) · Cell

Nuclear Structure and FunctionMicrotubule and mitosis dynamics

Cited by 741

Identification of long-lived proteins reveals exceptional stability of essential cellular structures

Toyama, B. H., Savas, J. N., Park, S. K., Harris, M. S., Ingolia, N. T., Yates, J. R., & Hetzer, M. W. (2013) · Cell

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

Cited by 572

Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.

D'Angelo, M. A., Raices, M., Panowski, S. H., & Hetzer, M. W. (2009) · Cell

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

Cited by 565

Extremely long-lived nuclear pore proteins in the rat brain

Savas, J. N., Toyama, B. H., Xu, T., Yates, J. R., & Hetzer, M. W. (2012) · Science

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

Cited by 335

Nucleolar expansion and elevated protein translation in premature aging

Buchwalter, A., & Hetzer, M. W. (2017) · Nature Communications

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

Cited by 263

Predicting age from the transcriptome of human dermal fibroblasts

Fleischer, J. G., Schulte, R., Tsai, H. H., Tyagi, S., Ibarra, A., Shokhirev, M. N., Huang, L., Hetzer, M. W., & Navlakha, S. (2018) · Genome Biology

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 232

Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats

Ori, A., Toyama, B. H., Harris, M. S., Bock, T., Iskar, M., Bork, P., Ingolia, N. T., Hetzer, M. W., & Beck, M. (2015) · Cell Systems

Genetics, Aging, and Longevity in Model OrganismsAdvanced Proteomics Techniques and Applications

Cited by 201

Age mosaicism across multiple scales in adult tissues

Arrojo e Drigo, R., Lev-Ram, V., Tyagi, S., Ramachandra, R., Deerinck, T., Bushong, E., Phan, S., Orphan, V., Lechene, C., Ellisman, M. H., et al. (2019) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 137

Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain

Krishna, S., Arrojo e Drigo, R., Capitanio, J. S., Ramachandra, R., Ellisman, M., & Hetzer, M. W. (2021) · Developmental Cell

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 73