Hamilton, Thomas

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease

Qian, Y., Liu, C., Hartupee, J., Altuntas, C. Z., Gulen, M. F., Jane-wit, D., Xiao, J., Lu, Y., Giltiay, N., Liu, J., et al. (2007) · Nature Immunology

Psoriasis: Treatment and PathogenesisNF-κB Signaling Pathways

Cited by 614

Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis

Ransohoff, R. M., Hamilton, T. A., Tani, M., Stoler, M. H., Shick, H. E., Major, J. A., Estes, M. L., Thomas, D. M., & Tuohy, V. K. (1993) · The FASEB Journal

Multiple Sclerosis Research StudiesChemokine receptors and signaling

Cited by 496

Synergy between Interferon-γ and Tumor Necrosis Factor-α in Transcriptional Activation Is Mediated by Cooperation between Signal Transducer and Activator of Transcription 1 and Nuclear Factor κB

Ohmori, Y., Schreiber, R. D., & Hamilton, T. A. (1997) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 413

Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

Sun, D., Novotny, M., Bulek, K., Liu, C., Li, X., & Hamilton, T. (2011) · Nature Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 232

The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

Bulek, K., Liu, C., Swaidani, S., Wang, L., Page, R. C., Gulen, M. F., Herjan, T., Abbadi, A., Qian, W., Sun, D., et al. (2011) · Nature Immunology

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 192

IL-4-induced STAT6 suppresses IFN-gamma-stimulated STAT1-dependent transcription in mouse macrophages

Ohmori, Y., & Hamilton, T. A. (1997) · The Journal of Immunology

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 161

IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling

Herjan, T., Hong, L., Bubenik, J., Bulek, K., Qian, W., Liu, C., Li, X., Chen, X., Yang, H., Ouyang, S., et al. (2018) · Nature Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 121

Interleukin-4/STAT6 Represses STAT1 and NF-κB-dependent Transcription through Distinct Mechanisms

Ohmori, Y., & Hamilton, T. A. (2000) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 106

IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells

Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C.-J., Ko, J., Zhu, L., et al. (2019) · Journal of Experimental Medicine

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 106

HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization

Herjan, T., Yao, P., Qian, W., Li, X., Liu, C., Bulek, K., Sun, D., Yang, W.-P., Zhu, J., He, A., et al. (2013) · The Journal of Immunology

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 95

IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence

Datta, S., Novotny, M., Pavicic, P. G., Zhao, C., Herjan, T., Hartupee, J., & Hamilton, T. (2010) · The Journal of Immunology

RNA Research and SplicingChemokine receptors and signaling

Cited by 82

Lipopolysaccharide Induces Formyl Peptide Receptor 1 Gene Expression in Macrophages and Neutrophils via Transcriptional and Posttranscriptional Mechanisms

Mandal, P., Novotny, M., & Hamilton, T. A. (2005) · The Journal of Immunology

Immune Response and InflammationChemokine receptors and signaling

Cited by 45

Cell type- and stimulus-specific mechanisms for post-transcriptional control of neutrophil chemokine gene expression

Hamilton, T., Li, X., Novotny, M., Pavicic, P. G., Datta, S., Zhao, C., Hartupee, J., & Sun, D. (2011) · Journal of Leukocyte Biology

RNA Research and SplicingChemokine receptors and signaling

Cited by 32