Rosen, Michael K.

A framework for understanding the functions of biomolecular condensates across scales

Lyon, A. S., Peeples, W. B., & Rosen, M. K. (2021) · Nature Reviews Molecular Cell Biology

RNA Research and SplicingNuclear Structure and Function

Cited by 895

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

Harmon, T. S., Holehouse, A. S., Rosen, M. K., & Pappu, R. V. (2017) · eLife

RNA Research and SplicingProtein Structure and Dynamics

Cited by 713

Structure and control of the actin regulatory WAVE complex

Chen, Z., Borek, D., Padrick, S. B., Gomez, T. S., Metlagel, Z., Ismail, A. M., Umetani, J., Billadeau, D. D., Otwinowski, Z., & Rosen, M. K. (2010) · Nature

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 500

The WAVE regulatory complex links diverse receptors to the actin cytoskeleton

Chen, B., Brinkmann, K., Chen, Z., Pak, C. W., Liao, Y., Shi, S., Henry, L., Grishin, N. V., Bogdan, S., & Rosen, M. K. (2014) · Cell

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 323

Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites

Chen, B., Chou, H.-T., Brautigam, C. A., Xing, W., Yang, S., Henry, L., Doolittle, L. K., Walz, T., & Rosen, M. K. (2017) · eLife

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 173

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

Yu, B., Martins, I. R. S., Li, P., Amarasinghe, G. K., Umetani, J., Fernandez-Zapico, M. E., Billadeau, D. D., Machius, M., Tomchick, D. R., & Rosen, M. K. (2010) · Cell

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 156

Structure and mutagenesis of the Dbl homology domain

Aghazadeh, B., Zhu, K., Kubiseski, T. J., Liu, G. A., Pawson, T., Zheng, Y., & Rosen, M. K. (1998) · Nature Structural Biology

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 145

Local F-actin Network Links Synapse Formation and Axon Branching

Chia, P. H., Chen, B., Li, P., Rosen, M. K., & Shen, K. (2014) · Cell

Neuroscience and Neuropharmacology ResearchAxon Guidance and Neuronal Signaling

Cited by 145

Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

Srinivasan, N., Gordon, O., Ahrens, S., Franz, A., Deddouche, S., Chakravarty, P., Phillips, D., Yunus, A. A., Rosen, M. K., Valente, R. S., et al. (2016) · eLife

Invertebrate Immune Response MechanismsImmune Response and Inflammation

Cited by 69