A framework for understanding the functions of biomolecular condensates across scales

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

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Biomolecular condensates: organizers of cellular biochemistry

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Stochastic Gene Expression in a Single Cell

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Liquid phase condensation in cell physiology and disease

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Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

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Liquid-Liquid Phase Separation in Biology

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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

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Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

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Coactivator condensation at super-enhancers links phase separation and gene control

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Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

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Phase transitions in the assembly of multivalent signalling proteins

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Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

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Decoding ALS: from genes to mechanism

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Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

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Cohesin Loss Eliminates All Loop Domains

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A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins

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Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

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Phase separation drives heterochromatin domain formation

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Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

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Coexisting liquid phases underlie nucleolar sub-compartments

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53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

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ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

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Regulation of noise in the expression of a single gene

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Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

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CO<b>₂</b> CONCENTRATING MECHANISMS IN ALGAE: Mechanisms, Environmental Modulation, and Evolution

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Functional roles for noise in genetic circuits

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Polymer physics of intracellular phase transitions

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Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

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The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

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Phase separation of signaling molecules promotes T cell receptor signal transduction

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Compositional Control of Phase-Separated Cellular Bodies

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G3BP1 is a tunable switch that triggers phase separation to assemble stress granules

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Valence and patterning of aromatic residues determine the phase behavior of prion-like domains

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DNA-induced liquid phase condensation of cGAS activates innate immune signaling

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The nucleolus as a multiphase liquid condensate

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The Presynaptic Active Zone

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Organization of Chromatin by Intrinsic and Regulated Phase Separation

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Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells

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Imaging dynamic and selective low-complexity domain interactions that control gene transcription

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Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response

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RNA phase transitions in repeat expansion disorders

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FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

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Pi-Pi contacts are an overlooked protein feature relevant to phase separation

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Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

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Ewing sarcoma

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RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

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Liquid–Liquid Phase Separation in Disease

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Experimental evolution

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P-Body Purification Reveals the Condensation of Repressed mRNA Regulons

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Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

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The Organization of Replication and Transcription

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Single-Molecule Microscopy Reveals Plasma Membrane Microdomains Created by Protein-Protein Networks that Exclude or Trap Signaling Molecules in T Cells

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High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

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Phase separation of a yeast prion protein promotes cellular fitness

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Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

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Processing bodies require RNA for assembly and contain nontranslating mRNAs

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P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

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CO₂ CONCENTRATING MECHANISMS IN PHOTOSYNTHETIC MICROORGANISMS

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Composition-dependent thermodynamics of intracellular phase separation

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The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin

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Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity

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Axonal transport: cargo-specific mechanisms of motility and regulation

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Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome

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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

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G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

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Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation

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The regulation, functions and clinical relevance of arginine methylation

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Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles

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Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

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Evaluating phase separation in live cells: diagnosis, caveats, and functional consequencesPreprint

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Phase transitions of multivalent proteins can promote clustering of membrane receptors

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Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

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Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II

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Microtubule dynamics: an interplay of biochemistry and mechanics

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Structure and function of Rubisco

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Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes.

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RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

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RNA polymerase II clustering through carboxy-terminal domain phase separation

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mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding

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The Central Dogma Decentralized: New Perspectives on RNA Function and Local Translation in Neurons

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Translation Repression in Human Cells by MicroRNA-Induced Gene Silencing Requires RCK/p54

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Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation

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mRNA structure determines specificity of a polyQ-driven phase separation

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Partitioning of cancer therapeutics in nuclear condensates

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