Lean, Michael E. J.

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial

Lean, M. E., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Peters, C., Zhyzhneuskaya, S., Al-Mrabeh, A., Hollingsworth, K. G., et al. (2018) · The Lancet

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 2,095

Waist circumference as a measure for indicating need for weight management

Lean, M. E. J., Han, T. S., & Morrison, C. E. (1995) · BMJ

Body Composition Measurement TechniquesObesity, Physical Activity, Diet

Cited by 1,869

Identification of late-onset hypogonadism in middle-aged and elderly men

Wu, F. C. W., Tajar, A., Beynon, J. M., Pye, S. R., Silman, A. J., Finn, J. D., O'Neill, T. W., Bartfai, G., Casanueva, F. F., Forti, G., et al. (2010) · New England Journal of Medicine

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 1,544

Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study

Astrup, A., Rössner, S., Van Gaal, L., Rissanen, A., Niskanen, L., Al Hakim, M., Madsen, J., Rasmussen, M. F., & Lean, M. E. (2009) · The Lancet

Pharmacology and Obesity TreatmentRegulation of Appetite and Obesity

Cited by 1,163

Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial

Lean, M. E. J., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Peters, C., Zhyzhneuskaya, S., Al-Mrabeh, A., Hollingsworth, K. G., et al. (2019) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,017

3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial

le Roux, C. W., Astrup, A., Fujioka, K., Greenway, F., Lau, D. C. W., Van Gaal, L., Ortiz, R. V., Wilding, J. P. H., Skjøth, T. V., Manning, L. S., et al. (2017) · The Lancet

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 850

Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evidence from the European Male Ageing Study

Tajar, A., Forti, G., O'Neill, T. W., Lee, D. M., Silman, A. J., Finn, J. D., Bartfai, G., Boonen, S., Casanueva, F. F., Giwercman, A., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 604

Coffee: Biochemistry and Potential Impact on Health

Ludwig, I. A., Clifford, M. N., Lean, M. E. J., Ashihara, H., & Crozier, A. (2014) · Food Funct.

Coffee research and impactsGenomics, phytochemicals, and oxidative stress

Cited by 537

Remission of human type 2 diabetes requires decrease in liver and pancreas fat content but is dependent upon capacity for β cell recovery

Taylor, R., Al-Mrabeh, A., Zhyzhneuskaya, S., Peters, C., Barnes, A. C., Aribisala, B. S., Hollingsworth, K. G., Mathers, J. C., Sattar, N., & Lean, M. E. J. (2018) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 450

Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European male ageing study

Camacho, E. M., Huhtaniemi, I. T., O'Neill, T. W., Finn, J. D., Pye, S. R., Lee, D. M., Tajar, A., Bartfai, G., Boonen, S., Casanueva, F. F., et al. (2013) · European Journal of Endocrinology

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 392

Obesity and weight management in the elderly

Han, T. S., Tajar, A., & Lean, M. E. J. (2011) · British Medical Bulletin

Nutrition and Health in AgingObesity, Physical Activity, Diet

Cited by 327

Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS)

Tajar, A., Huhtaniemi, I. T., O'Neill, T. W., Finn, J. D., Pye, S. R., Lee, D. M., Bartfai, G., Boonen, S., Casanueva, F. F. F., Forti, G., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesMenopause: Health Impacts and Treatments

Cited by 318

Evidence-based European recommendations for the dietary management of diabetes

The Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD), Aas, A.-M., Axelsen, M., Churuangsuk, C., Hermansen, K., Kendall, C. W. C., Kahleova, H., Khan, T., Lean, M. E. J., Mann, J. I., et al. (2023) · Diabetologia

Nutritional Studies and DietDiabetes Management and Education

Cited by 262

Variations in Caffeine and Chlorogenic Acid Contents of Coffees: What Are We Drinking?

Ludwig, I. A., Mena, P., Calani, L., Cid, C., Del Rio, D., Lean, M. E. J., & Crozier, A. (2014) · Food Funct.

Coffee research and impactsPhytochemicals and Antioxidant Activities

Cited by 226

Brown adipose tissue uncoupling protein content in human infants, children and adults

Lean, M. E. J., James, W. P. T., Jennings, G., & Trayhurn, P. (1986) · Clinical Science

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 213

Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults

on behalf of the NN8022-1807 Investigators, Lean, M. E. J., Carraro, R., Finer, N., Hartvig, H., Lindegaard, M. L., Rössner, S., Van Gaal, L., & Astrup, A. (2014) · International Journal of Obesity

Pharmacology and Obesity TreatmentDiabetes Treatment and Management

Cited by 210

Diets for weight management in adults with type 2 diabetes: an umbrella review of published meta-analyses and systematic review of trials of diets for diabetes remission

Churuangsuk, C., Hall, J., Reynolds, A., Griffin, S. J., Combet, E., & Lean, M. E. J. (2022) · Diabetologia

Diet and metabolism studiesDiabetes Treatment and Management

Cited by 204

Association of hypogonadism with vitamin D status: The European Male Ageing Study

Lee, D. M., Tajar, A., Pye, S. R., Boonen, S., Vanderschueren, D., Bouillon, R., O'Neill, T. W., Bartfai, G., Casanueva, F. F., Finn, J. D., et al. (2012) · European Journal of Endocrinology

Hormonal and reproductive studiesVitamin D Research Studies

Cited by 196

5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study

Lean, M. E., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Kelly, T., Irvine, K., Peters, C., Zhyzhneuskaya, S., et al. (2024) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementBariatric Surgery and Outcomes

Cited by 186

Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone

Antonio, L., Wu, F. C. W., O'Neill, T. W., Pye, S. R., Ahern, T. B., Laurent, M. R., Huhtaniemi, I. T., Lean, M. E. J., Keevil, B. G., Rastrelli, G., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesSperm and Testicular Function

Cited by 174

Weight gain as an adverse effect of some commonly prescribed drugs: a systematic review

Leslie, W. S., Hankey, C. R., & Lean, M. E. J. (2007) · QJM

Pharmacology and Obesity TreatmentObesity and Health Practices

Cited by 173

Effect of a lifestyle intervention on weight change in south Asian individuals in the UK at high risk of type 2 diabetes: a family-cluster randomised controlled trial

Bhopal, R. S., Douglas, A., Wallia, S., Forbes, J. F., Lean, M. E. J., Gill, J. M. R., McKnight, J. A., Sattar, N., Sheikh, A., Wild, S. H., et al. (2014) · The Lancet Diabetes & Endocrinology

Diabetes, Cardiovascular Risks, and LipoproteinsObesity, Physical Activity, Diet

Cited by 149

Effect of three treatment schedules of recombinant methionyl human leptin on body weight in obese adults: a randomized, placebo‐controlled trial

Zelissen, P. M. J., Stenlof, K., Lean, M. E. J., Fogteloo, J., Keulen, E. T. P., Wilding, J., Finer, N., Rössner, S., Lawrence, E., Fletcher, C., et al. (2005) · Diabetes, Obesity and Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 144

2-year remission of type 2 diabetes and pancreas morphology: a post-hoc analysis of the DiRECT open-label, cluster-randomised trial

Al-Mrabeh, A., Hollingsworth, K. G., Shaw, J. A. M., McConnachie, A., Sattar, N., Lean, M. E. J., & Taylor, R. (2020) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 122