Segal, Eran

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

Tsai, M.-C., Manor, O., Wan, Y., Mosammaparast, N., Wang, J. K., Lan, F., Shi, Y., Segal, E., & Chang, H. Y. (2010) · Science

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 3,290

Personalized nutrition by prediction of glycemic responses

Zeevi, D., Korem, T., Zmora, N., Israeli, D., Rothschild, D., Weinberger, A., Ben-Yacov, O., Lador, D., Avnit-Sagi, T., Lotan-Pompan, M., et al. (2015) · Cell

Nutrition, Genetics, and DiseaseDiabetes Management and Research

Cited by 2,929

Environment dominates over host genetics in shaping human gut microbiota

Rothschild, D., Weissbrod, O., Barkan, E., Kurilshikov, A., Korem, T., Zeevi, D., Costea, P. I., Godneva, A., Kalka, I. N., Bar, N., et al. (2018) · Nature

Gut microbiota and healthGenetic Associations and Epidemiology

Cited by 2,859

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

Nejman, D., Livyatan, I., Fuks, G., Gavert, N., Zwang, Y., Geller, L. T., Rotter-Maskowitz, A., Weiser, R., Mallel, G., Gigi, E., et al. (2020) · Science

Gut microbiota and healthBacterial Cancer Therapy

Cited by 2,464

The role of site accessibility in microRNA target recognition

Kertesz, M., Iovino, N., Unnerstall, U., Gaul, U., & Segal, E. (2007) · Nature Genetics

MicroRNA in disease regulationRNA and protein synthesis mechanisms

Cited by 2,460

Role of the gut microbiota in nutrition and health

Valdes, A. M., Walter, J., Segal, E., & Spector, T. D. (2018) · BMJ

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 2,375

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

Suez, J., Korem, T., Zeevi, D., Zilberman-Schapira, G., Thaiss, C. A., Maza, O., Israeli, D., Zmora, N., Gilad, S., Weinberger, A., et al. (2014) · Nature

Gut microbiota and healthBiochemical Analysis and Sensing Techniques

Cited by 2,067

Large-scale association analyses identify host factors influencing human gut microbiome composition

Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., et al. (2021) · Nature Genetics

Gut microbiota and healthGenetic Associations and Epidemiology

Cited by 1,786

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

Zmora, N., Zilberman-Schapira, G., Suez, J., Mor, U., Dori-Bachash, M., Bashiardes, S., Kotler, E., Zur, M., Regev-Lehavi, D., Brik, R. B.-Z., et al. (2018) · Cell

Probiotics and Fermented FoodsGut microbiota and health

Cited by 1,695

Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis

Thaiss, C. A., Zeevi, D., Levy, M., Zilberman-Schapira, G., Suez, J., Tengeler, A. C., Abramson, L., Katz, M. N., Korem, T., Zmora, N., et al. (2014) · Cell

Gut microbiota and healthCircadian rhythm and melatonin

Cited by 1,449

The pros, cons, and many unknowns of probiotics

Suez, J., Zmora, N., Segal, E., & Elinav, E. (2019) · Nature Medicine

Probiotics and Fermented FoodsGut microbiota and health

Cited by 1,398

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

Suez, J., Zmora, N., Zilberman-Schapira, G., Mor, U., Dori-Bachash, M., Bashiardes, S., Zur, M., Regev-Lehavi, D., Ben-Zeev Brik, R., Federici, S., et al. (2018) · Cell

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 1,184

Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling

Levy, M., Thaiss, C. A., Zeevi, D., Dohnalová, L., Zilberman-Schapira, G., Mahdi, J. A., David, E., Savidor, A., Korem, T., Herzig, Y., et al. (2015) · Cell

Gut microbiota and healthInflammasome and immune disorders

Cited by 960

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations

Thaiss, C. A., Levy, M., Korem, T., Dohnalová, L., Shapiro, H., Jaitin, D. A., David, E., Winter, D. R., Gury-BenAri, M., Tatirovsky, E., et al. (2016) · Cell

Gut microbiota and healthCircadian rhythm and melatonin

Cited by 870

Prediction of acute myeloid leukaemia risk in healthy individuals

Abelson, S., Collord, G., Ng, S. W. K., Weissbrod, O., Mendelson Cohen, N., Niemeyer, E., Barda, N., Zuzarte, P. C., Heisler, L., Sundaravadanam, Y., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 850

Potential roles of gut microbiome and metabolites in modulating ALS in mice

Blacher, E., Bashiardes, S., Shapiro, H., Rothschild, D., Mor, U., Dori-Bachash, M., Kleimeyer, C., Moresi, C., Harnik, Y., Zur, M., et al. (2019) · Nature

Gut microbiota and healthAmyotrophic Lateral Sclerosis Research

Cited by 700

A module map showing conditional activity of expression modules in cancer

Segal, E., Friedman, N., Koller, D., & Regev, A. (2004) · Nature Genetics

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 685

Decoding global gene expression programs in liver cancer by noninvasive imaging

Segal, E., Sirlin, C. B., Ooi, C., Adler, A. S., Gollub, J., Chen, X., Chan, B. K., Matcuk, G. R., Barry, C. T., Chang, H. Y., et al. (2007) · Nature Biotechnology

Radiomics and Machine Learning in Medical ImagingMedical Imaging Techniques and Applications

Cited by 629

Landscape and variation of RNA secondary structure across the human transcriptome

Wan, Y., Qu, K., Zhang, Q. C., Flynn, R. A., Manor, O., Ouyang, Z., Zhang, J., Spitale, R. C., Snyder, M. P., Segal, E., et al. (2014) · Nature

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 555

Persistent microbiome alterations modulate the rate of post-dieting weight regain

Thaiss, C. A., Itav, S., Rothschild, D., Meijer, M. T., Levy, M., Moresi, C., Dohnalová, L., Braverman, S., Rozin, S., Malitsky, S., et al. (2016) · Nature

Gut microbiota and healthRegulation of Appetite and Obesity

Cited by 471

Motif module map reveals enforcement of aging by continual NF-κB activity

Adler, A. S., Sinha, S., Kawahara, T. L. A., Zhang, J. Y., Segal, E., & Chang, H. Y. (2007) · Genes & Development

Genetics, Aging, and Longevity in Model OrganismsGenomics and Chromatin Dynamics

Cited by 466

Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters

Sharon, E., Kalma, Y., Sharp, A., Raveh-Sadka, T., Levo, M., Zeevi, D., Keren, L., Yakhini, Z., Weinberger, A., & Segal, E. (2012) · Nature Biotechnology

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 457

Identification of bacteria-derived HLA-bound peptides in melanoma

Kalaora, S., Nagler, A., Nejman, D., Alon, M., Barbolin, C., Barnea, E., Ketelaars, S. L. C., Cheng, K., Vervier, K., Shental, N., et al. (2021) · Nature

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 457

Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome

Mars, R. A. T., Yang, Y., Ward, T., Houtti, M., Priya, S., Lekatz, H. R., Tang, X., Sun, Z., Kalari, K. R., Korem, T., et al. (2020) · Cell

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 456